Iodine and thyroid

That lack of specific substances, as it turned out, iodine, causing the disease, later called graves ' disease, were written in the Indian Vedas, in the old Testament in ancient Chinese books... even Know how to treat as patients gave the ashes of the burnt sea sponges, which contains iodine. But the element was opened by chance only in 1811 Courtois, when he on the orders of Napoleon looked for new sources of raw materials among marine plants. Only in 1896 Bauman found iodine in the thyroid gland and confirmed by the fact that in graves ' disease of iodine in it is too little. In 1914 Kendal allocated from the thyroid gland of myrotoxin, chemical formula of which was derived twelve years later, and then he was first sintezirovan. And in 1917 became widely known case of death of thousands of pigs in Montana in the United States because of a lack of iodine. After all, "thyroid gland" hurt not only people but also animals: dogs, sheep, horses, pigs, cattle, rabbits, fish.
Soon began to laderoute table salt in areas where this item was missing. It was also suggested to include in the diet of sea fish, which contains a lot of iodine, and to exclude plants containing substances, promote the development of graves ' disease.
Why in some areas of iodine too little? The fact that his connection is easily soluble in water, and in the mountains or in the rocky areas they simply wash away the rain and the water flows.
In Japan is relatively little iodine in the water and in the air, and soil, but the locals eat a lot of fish and seafood", rich that element. Taiwan, on the contrary, traditionally not eat "gifts of the sea", and graves ' disease there often is not even helps the iodization of drinking water.
In Poland the lack of iodine once very much felt in the South, in the Podkarpackie region. In 1932, for example, it was found that 15.5% of conscripts from the former Krakow Voivodeship had graves ' disease, and in the Western provinces due to the lack of iodine only 0.1 % of draftees were unhealthy.
In 1930, in the Podkarpackie region began to laderoute salt, and by 1938 graves ' disease was discovered only 2.9 % of conscripts. During the war stopped laderoute salt, and again broke out almost endemic diseases (in 1946 in two counties was sick 37 % of the population). Three years later it was already half the patients, although salt is not always properly audirovala. We must not forget that children of women, patients with graves ' disease, often there is a delay of development, cretinism, born dwarfs, etc., There is a hypothesis that cries patients cretinism shepherds from the mountains of Tyrol marked the beginning of what we call a "play the Tyrolean lad". The lack of this element, in addition to graves ' disease or mentally challenged, can cause changes in the chromosomes and to facilitate the emergence of cancer.
As it turned out, the spread of graves ' disease depends not only from a lack of iodine in the soil and vegetation, but also from a lack of cobalt. In 1961, the scientists of Kolomentsev and Gabovich examined the population of Altay territory. They concluded that the excess of cobalt also affects the thyroid gland. If cobalt too much, the iodine content in the blood decreases.
The amount of iodine in plants depends not only on the content of this element in the soil, but also on the ability of a species to concentrate it. Some plants contain certain substances that cause graves ' disease. It found szczesny in 1928 Guinea pigs fed cabbage leaves, and they had signs of the disease. When they started to give iodine, were to be settled metabolism, disappeared and other symptoms improper functioning of the thyroid gland. Further research has revealed some vegetables (cruciferous) nitrites and nitrates, which can turn into nitrosamines. Acamprosate nitrosamines and cause an increase in the thyroid gland. It also turned out that excess consumption of soy causes an enlargement of the thyroid gland (sometimes five), increases the need for iodine is 100%. Later it turned out that there are many different compounds that have a similar effect, for example, some sulfa drugs, including popular in Poland sulfaguanidine (remedy for upset stomach, already removed from production). All these graves ' disease-causing factors are the stronger, the smaller of iodine in the environment and food products.