Albumin - globulin ratio

Albumin - globulin ratio - the ratio of albumin and globulins blood, the value of the norm is relatively constant (1,5-2,3). When determining albumin - globulin ratio usually use the method of vysalivaniya, using differences in solubility of albumins and globulins, or by electrophoresis serum (see Electrophoresis). The decrease albumin - globulin ratio, typical of many pathological conditions may be due to both the increase globulin fraction (acute infections, a chronic inflammatory processes)and decreasing the amount of albumin (cirrhosis, hepatitis and other liver diseases).

Albumin - globulin ratio - the ratio of the number of albumin to globulins in the blood serum; in the norm is 1.5 to 2.3. Determination of albumin and globulins produced with the assistance of nephelometry (see), refractometry (see), electrophoretic methods of research (see Electrophoresis). Sharp reduction of the content of albumin (decrease albumin-globulin ratio), with a concomitant decrease in total protein in the serum when malnutrition, amyloid principally with long albuminuria, portal cirrhosis of the liver. Content increased globulins (decrease A.-G. K.) with a significant increase in the content of total protein in the serum in myeloma, visceral leishmaniasis. The decrease A.-G. K. (without increasing the number of total protein blood serum) is observed at a number of infectious diseases, severe liver disease (hepatitis, cirrhosis), and collagen diseases, with some lesions of blood-forming organs.