Aldosteronism is a clinical syndrome associated with increased formation in the body of the hormone aldosterone napochechnikov. Distinguish between primary and secondary aldosteronism. Primary aldosteronism (syndrome horse) occurs when tumors of the adrenal gland. It is manifested by the increase of arterial pressure, a change in mineral metabolism (in the blood decreases sharply content of potassium), muscle weakness, seizures and convulsions, increased secretion of aldosterone in the urine. Secondary aldosteronism is associated with increased secretion of aldosterone normal adrenal glands as a result of excessive incentives governing its secretion. It occurs in heart failure, some forms of chronic nephritis and liver cirrhosis. Mineral metabolism in secondary aldosteronism accompanied by the development of edema. Kidney damage aldosteronism increases hypertension. Treatment of primary aldosteronism surgery: removal of the tumor of the adrenal glands leads to recovery. In secondary aldosteronism along with treatment of the disease that caused the aldosteronism, appoint aldosterone blockers (aldactone 100 - 200 mg 4 times a day inside during the week), prednisolone, diuretics.

Aldosteronism is a complex of changes in the body, caused by increased secretion of aldosterone. Aldosteronism may be primary or secondary. Primary aldosteronism (syndrome horse) is caused by the overproduction of aldosterone hormone active tumor of the adrenal gland. Clinically expressed hypertension, muscle weakness, seizures and convulsions, polyuria, a sharp decrease in the content of potassium in the serum and increased secretion of aldosterone from the urine; swelling usually does not happen. The tumor results in lowering blood pressure and normalization of electrolytes.
Secondary aldosteronism caused by breaking regulating the secretion of aldosterone in glomerular area of the adrenal glands. The decrease in the volume of intravascular pathology (as a result of the hemodynamic disorders, gipoproteinemii or changes in the concentration of electrolytes in the blood serum), increased renin secretion, adrenocorticotropin, ACTH leads to hypersecretion of aldosterone. Secondary aldosteronism is observed in heart failure (stagnation), cirrhosis of the liver, swollen and puffy-hypertensive forms of chronic diffuse glomerulonephritis. The high content of aldosterone in these cases is increased reabsorption of sodium in the renal tubules and thereby can contribute to the development of edema. In addition, increased secretion of aldosterone in hypertensive form of diffuse glomerulonephritis, pyelonephritis or occlusive lesions of the renal arteries, as well as in hypertensive disease in the later stages of its development and malignant option, the current leads to the redistribution of electrolytes in the walls of the arterioles and to the strengthening of hypertension. Suppressing action of aldosterone level of the renal tubules is achieved by using his antagonist - aldactone on 400-800 mg per day per os during the week (under the control of the allocation of electrolytes with urine), in combination with the usual diuretic drugs. To suppress the secretion of aldosterone (with puffy and swollen-hypertensive forms of chronic diffuse glomerulonephritis, liver cirrhosis) designate prednisolone.