Amyloid tumor

Amyloid tumor (synonym granulomas amyloidosis) - isolated local amyloidosis, a kind of primary atypical of amyloidosis. Observed mainly in men occurs in the age of from 11 up to 80 years, but more often - from 50 to 70 years. Frequency localization in the first place are the larynx ("polyps"), language (with the picture of macroglossia), trachea, nose throat, bronchi and lungs. Less amyloid the tumor is localized in the skin, the gastrointestinal tract (amyloid deposited in the submucosal layer of the intestine; formed single or multiple adenomatous "polyps", which for a considerable amount of amyloid deposits can lead to phenomena of mechanical obstruction), in the thyroid gland (the so-called amyloid goiter with symptoms of hypothyroidism), in centuries, lymph nodes, urinary tract, bones.
The etiology is unclear.
Granulomas amyloidosis can be knotted, single or multiple (so-called polyps), diffuse (often in the bronchial tree). Microscopically in the area of deposits of amyloid there are a plethora and enlargement of the lymph vessels. The deposition of amyloid accompanied giant cell reaction; often among the masses of amyloid found bone and cartilage. It is possible that the development of local amyloidosis linked with local violations lymph circulation. The content in the cytoplasm of giant cells chondroitinase acid suggests that they are involved in the production of amyloid. However, it is possible that the amyloid resolves these giant cells. Diagnosed amyloid the tumor using only biopsy.
Treatment of tumor - operative. Relapses after removal has never been observed. Radiotherapy unsuccessful. The effectiveness of hormonal therapy (ACTH and cortisone), in combination with vitamin (vitamin E) - relative. Cm. also Amyloidosis.