Antibiotics animal

A story of antibiotics in animal tissues old. At the end of last century one of the founders of the Russian microbiological school N. F. gamaleja was first pointed out that the Bacillus of anthrax lose some biochemical properties and change their morphology under the action of the extract from the spleen. These observations formed the basis of subsequent experiments N. F. gamaleja, proposed for the treatment of some forms of tuberculosis apply tissue extracts.
The most important observations about antibiotics animal origin, were made in 1892 D. M. assumption, which found that extracts of tissue have antimicrobial effect on pathogens of anthrax and glanders. Extracts of organisms of animals were used with great success to treat animals experimentally infected with anthrax.
Antibacterial substance lysozyme was opened in the egg white in 1909 by the Russian scientist N. M. Lesenkova and later described by Fleming.
In 1927 3. Century ermoleva and I. S. Buyanovskaya studied and first used lysozyme with a practical purpose. It was found in the liver, cartilage, spleen, saliva and tears. In the production of lysozyme extracted from egg whites. The drug was effective at diseases of ear, throat, nose and eyes.
In industry lysozyme use for conservation of eggs and milk, and in agriculture, for flax fiber quality.
Among antibiotics animal greatest distribution was received by akmolin allocated 3. C. Ermolovoy and L. K. Valedynsky in 1949 from Molok sturgeon. Akmolin available in the form of 0.5% solution in water. He has both antibacterial and antiviral effect.
Akmolin was the first antibiotic, delaying the development of influenza virus in the experiment, and the only drug that acts on the influenza virus in humans. Akmolin facilitates and shortens the period of influenza.
To ensure borne complications in acute upper respiratory catarrh, akmolin is used in combination with penicillin and tetracycline antibiotics. And it is not only enhances the antimicrobial activity of these antibiotics, but also prevents resistant to these antibiotics microorganisms and prevents the formation of resistant microbes.
With a combination of akmolina with tetracycline antibiotics in most patients is not observed side effects as nausea, vomiting and diarrhea. Akmolin became part of the new medical preparations of antibiotics, as economically I and II and penicillin-ecmo.