Antipain is modified vaccine composed of substances released from microbial bodies when heated, in a subsequent filtered and can phenol.
Currently staphylococcal antipain made from 10-12 different strains of Golden and white Staphylococcus.
The mechanism of therapeutic action of antipain associated mainly with activation antimicrobial immunity and termination of bacteremia, and the desensitization of the organism to aureus and a General increase protective reaction to staphylococcic infection, such as the elaboration of specific antibodies and enhance phagocytosis. Phagocytic activity of leukocytes under the influence of antipain increases significantly, which is not always observed after immunization with toxoid. In this regard, the most appropriate combined treatment of the toxoid and antipirina, which experimental observations on animals also ensures the highest degree of rise of antivenoms.
Staphylococcal antipain is the filtrate specific soluble staphylococcal antigen released from ballast substances.
In the treatment of antipirina with daily injections due to sensitization may have more local reactions. Even in the absence of such reactions hardly makes sense every day to enter antipain, as a result of frequent injections of the preparation phase initiation may be followed by a phase of braking.
Fast therapeutic effect depends on the continuous effects on the inflammatory process. However, to ensure this continuous irritation simply enter antipain once in 5 days. In this regard, antipain better to enter once in 5 days at a dose of 0.5-1.0-2.0 ml (course - 3-4 injections). Best is a subcutaneous injection. The place of injection each time you should change that contributes to involvement in the process of reaching more of receptors.
Staphylococcal antipain has properties specific staphylococcal allergen. It is shown by its ability in subcutaneous introduction to cause temporary exacerbation of the inflammatory process in areas of specific injection.
Antipain not only provides therapeutic effect when staphylococcal defeats, but also can prevent disease recurrence. In patients antipirina rarely observed recurrent staphylococcal diseases, while at not receiving his relapses and various complications (otitis, pneumonia, sepsis) are noted frequently.
Antipain can serve not only as a therapeutic, prophylactic (especially in children and debilitated patients).