Basal cell carcinoma

Basal cell carcinoma is the most common epithelial tumours of the skin. Some authors regard it as a cancerthat's wrong, because it does not spreads; others - as a benign tumor that is also wrong because it destroys the surrounding tissue and recurs. Clinically basal cell carcinoma closer to malignant neoplasms. Correctly attributed the basalioma to tumors of a special kind, with masterstudium growth.
basal cell carcinomabasal cell carcinoma Arises more often on the face (Fig), mainly in old age. Usually a single tumor, however, may be plural. Basal cell carcinoma starts with dense painless nodules or plaques, which is gradually increasing, and then ulcerated. Sores around by a small roller compacted Boskovice pink or multiple small nodules. The bottom is covered with sores of dirty-grey or pink crust. Ulcers can rubtsevania in some parts, and to progress in others. The tumor grows slowly, over many years.
Surgical treatment - times (excision of the tumor with the help of special metal tip, through which the electric current of high frequency), electrocoagulation (see Diathermocoagulation) or radiation.

Basal cell carcinoma (synonym: basal cell cancer, basal cell epithelioma, karimkareem, carcinoid skin, rapidement epithelioma, ulcus rodens) - a tumor of the skin, originating from the basal layer of the epidermis or skin appendages. Sometimes a basal cell carcinoma is considered as dysontogenetic the tumor. The issue of histogenesis unclear. Increases basal cell carcinoma infiltrating growth, rarely spreads (in III-IV stage), so the prognosis is relatively good (tumor grows years). B. usually single (sometimes multiple), localized on the face, sometimes on the limbs or trunk, never on the palms, soles and mucous membranes. More often in middle and old age.
There are 4 form b: 1) nodular, papular, most often, in the center
sooner or later begins pitting; 2) ulcus rodens from the beginning occurs as ulcerative defect; 3) ulcus terebrans differs destructive growth; 4) flat superficial basal cell carcinoma of the skin. B. built from so-called dark cells with the basophilic cytoplasm and hyperchromic by the kernel, like cells in the basal layer of the epidermis. The mitoses rare. The histological structure of basal cell carcinoma is diverse and depends on the degree and direction of differentiation. The most frequent is undifferentiated solid b (Fig. 1). Tumor cells are jacks or cords. The border with the stroma the number of cells forms a fence; the cells in the center of the tumor complexes larger, lighter are randomly. In addition, there are cystic glandular form B.
Epidermoid more differentiated basal cell carcinoma, tumor cells accumulate keratohyalin and formed Horny pearls. In plodnih b cells form structures resembling the hair follicle. In pigment B. tumor cells contain a grain of melanin. Fibrosing B. has rough stroma. Cm. also Triovasalos.
flat superficial basal cell carcinoma of the skinFlat superficial basal cell carcinoma of the skin (synonym: pageCompany epithelioma, flat epitelioma trunk, multiple carcinoid skin, multiple erythematous epitelioma little) - type of basal cell carcinoma occurring streets of both sexes, usually over the age of 35-40 years. Plaques reddish color of various sizes, round, oval or irregular shape, with separate scales and bloody crusts on the surface, located on the trunk, less often on the face, yet at least on the limbs, being derived by merging of small pinhead knots. In the centre plaques nodules may regress, leaving and atrophic scar areas on the periphery form characteristic plotnosenow the border. Plaques can exist for years without ulceration, soak and any subjective symptoms. During benign. Occasionally plaques grow, izyaslau and surface B. in everyday invasive B.
Differential diagnosis with Bowen's disease, psoriasis, diskoidnaya red erythematosus, annular and atrophic lichen planus - is based primarily on the presence of characteristic aureole of knots, no ulceration. Because of the similarities are superficial basal cell carcinoma with named dermatoses crucial histological examination. Histologically found many multicenter emerging basal cell nests, which seem to be "suspended" to the epidermis (Fig. 2). Nests resemble ugly hair follicles, compact, sometimes with a gleam in the center. Cytologically surface B. no different from invasive. Tumor cells nests similar to the basal cells of epidermis, they are all similar kernel rich chromatin.
Treatment: the close-focus x-ray treatments, electrocoagulation, cryotherapy, surgical removal.