Beta therapy

Beta-therapy - radiation therapy electrons (beta-particles)emitted during beta decay of radioactive isotopes.
When the application beta-treatment to the affected areas of the body surface applied applicators, which are evenly distributed radioactive isotope of phosphorus (P32), thallium (Tl204) and others Use the application beta therapy for the treatment of capillary angiomas, with some chronic inflammatory diseases of the eye, leukoplakia mucosa. Other methods beta therapy used in malignant tumors.
Interstitial beta therapy carried out by typing in the tissue due to radiation, radioactive colloid solutions of gold (Au188), yttrium (Y90), silver (Ag111) or pins 3-4 mm length with isotope Au198 or Y90.
When intracavitary beta therapy colloidal solutions Au198 injected into the pleural or abdominal cavity after surgery about lung cancer, ovarian, stomach, intestines, for the impact on tumor microinsemination on the peritoneum, the ascites and pleural effusiondue to cancer metastasis, as well as for bladder cancer.
When diseases of the thyroid gland assign inside iodine preparations - J131, and at diseases of blood-forming organs - phosphorus - P32.
Cm. also Beta radiation, Isotopes (radioactive), Radiation therapy, Radioactive drugs.

Beta therapy is one of the methods of radiation therapy. The therapeutic effect of beta-therapy based on the biological action of beta-particles absorbed in pathologically changed tissues. As of radiation sources use different radioactive isotopes (see), the collapse of which emits beta particles. Depending on the method of summing of radiation sources to pathological nidus distinguish interstitial, intracavitary and application beta therapy.
Interstitial beta therapy is carried out by the infiltration of affected tissues colloidal solutions of radioactive isotopes or implantation in the tissue of radioactive pellets, ketotofin yarn, impregnated chemical compounds of beta-emitting isotopes, etc (see Radioactive drugs). The method shown in radioresistant forms of tumours. Uniform distribution of radioactive compounds in the tumor tissue is difficult, therefore there is a risk of non-homogeneous irradiation of the tumor. For the manufacture of radioactive products are short-lived radioactive isotopes with beta-radiation of high-energy (1 MeV and more). Due to the large penetrating power of high-energy beta particles inhomogeneity of irradiation of the tumor may be partially eliminated. For beta therapy using Au198, R, Ag111, Y90, etc.
Intracavitary beta therapy is carried out by introduction of colloidal solutions of radioactive isotopes in the body cavity of the patient. The greatest distribution of this method of treatment received at primary or secondary tumor defeat pleura or peritoneum, accompanied by effusions. Usually after removal from free oral liquid administered colloid solution activity 80-100 mkori for Au198 or Y90 and 15-25 km mkori for P32, previously dissolved in 100 ml of physiological solution. The uniform distribution of isotopes in the cavity is studied by using autoradiography (see), or scan (see).
Application of beta-therapy is conducted by applying to the affected areas of the body surface applicators. Use applicators, made of Plastic, the surface of which are evenly distributed radioactive isotopes closely connected with the Foundation of the applicator. For applicators use of radioactive isotopes with long half-lives b high energy beta particles (P32, Sr90 - Y90 and others). Treatment of fractional, 1-2 hour. in the day. Application of beta-therapy is indicated for eczema, neurodermatitis, eye diseases, leukoplakia mucosa, capillary hemangiomas, etc. It is also used in fungal skin. Therapeutic doses depend on the nature of the disease. Cm. also Radiation therapy.