Bigumal (Bigumalum; SYN. Proguanili hydrochloridum; FH, list B) - medical and preventive antimalarial drug. Bigumal. appoint 0.3 1 g once a day for 5 days. Bigumal low toxicity. Higher doses: single 0.3 g daily 0.6 to, the Form of release: white answers to 0.05 and 0.1 g; gray pill 0.1 grams of bigumal and 0.02 g of plasmacid or 0.05 g of bigumal and 0.01 g plasmacid; powder of bigumal for preparation of 1% solution for intravenous (only when comatose malaria). Keep in a dry, dark place. Cm. also Antimalarials.

Bigumal - antimalarial drug; hydrochloride N1-perchlorvinyl-N5-isopropyl-biguanida. Assign inside but 0.6 g (2 admission) in the first day and 0.3 g (at the reception) in the following days; you can combine bigumal with plasmozytom (see) or Akrikhin (see) and plasmozytom. When comatose form of malaria, bigumal injected (slowly) in the form of 1% solution in the dose of 0.15, Higher doses of bigumal for adults: inside - single 0.3 g daily 0.6 g, and intravenous - single 0.15 g daily - 0,45, Side effects: nausea, vomiting, short leukocytosis and the emergence of new forms of neutrophils; sometimes in the urine protein and red blood cells. Form of issue - powders and tablets 0.1 g of bigumal; 0.1 g of bigumal and 0.02 g plasmacid; 0.1 g of bigumal, 0.02 g plasmoid and 0.1 g of Akrikhin. Cm. also Antimalarials.