Bilirubinemia

Bilirubinemia (bilirubin + GK. haima, blood - the content of bilirubin in the blood plasma. OK, it is 0.2-0.6 mg% (by the method of van-den-Berg). Diagnostic value has hyperbilirubinemia, causing jaundice (see), if the content of bilirubin in the blood exceeds 1.5 - 2 mg%. The highest bilirubinemia (20-50 mg%) is observed in mechanical jaundice. Hemolytic jaundice occur less bilirubinemia - 2-7 mg% . The defeat parenhima liver (epidemic hepatitis, chronic hepatitis and others) are accompanied by moderate bilirubinemia (up to 15 mg%). Serum when bilirubinuria intensively painted in yellow. Methods of detection of bilirubin - see Ehrlich desireable. Cm. also Bilirubin, Bilirubinuria.

Bilirubinemia is the content of bilirubin in the blood. Hyperbilirubinemia is excessive levels of bilirubin in the blood. Normal serum contains up to 1 mg% bilirubin (different authors, depending on the method of the study lead to different values). Hyperbilirubinemia may depend on increasing the formation of pigment (hemolysis), and the violation of his release caused by obstruction to the flow of bile or decreasing ability of the liver to perceive bilirubin from the blood and excrete it in the bile ducts.
The jaundice of different origin in the blood can find different combinations of the three forms of bilirubin: not soluble in water free pigment, not giving with disreaction van den Berg immediate (direct) reaction and not passing in the urine; water-soluble bilirubinometry and diglucuronide giving a direct reaction van den Berg and can pass into the urine, and eviromentally bilirubin.
For differential diagnosis of diseases, accompanied by jaundice (see), it is important, in addition to the General content of bilirubin (see), to identify and its fractions.