Hlorbutin

Hlorbutin (Chlorbutinum; list a) - antineoplastic. Applied inside with chronic leukemia (mostly in leukemia forms) 0,002 - 0.01 g, depending on the number of leukocytes 1 mm3 blood, with chlamydia 0,003-0,002 grams per day; in the course of treatment (adult) not exceeding 0,35-0,4, the Highest single and daily doses of hlorbutin - 0,015 g
Hlorbutin contraindicated in severe liver disease and kidney, acute diseases of the gastrointestinal tract, immediately after the other cytotoxic drugs and radiation therapy, with pronounced leukopenia, thrombocytopenia and anemia associated with the development of malignant process.
The form of release: tablets and 0,005 0,002 g
Cm. also Antitumor agents.

Hlorbutin (Chlorbutinum; synonym: Chlorambucilum, Leukeran) - the anticancer drug; para-N-[di-(2-chloroethyl) AMINOPHENYL] butyric acid. Inhibitory effect of hlorbutin on lymphoid tissue was stronger than the effect on bone marrow. Hlorbutin used inside tablets for the treatment of Hodgkin's disease and chronic lymphocytic leukemia (leukemia and leikemicakie forms), with lymphosarcoma. For treatment of chlamydia given to adult daily dose of 15-20 mg for 3-4 weeks until leukopenia (3000). The second course in 1.5-2 months. Hlorbutin convenient for treatment of children, as almost does not cause nausea and vomiting. When limfoleikoze single dose of 8 -12 mg. Form of release: tablets on 2 and 5 mg
Cm. also Antitumor agents.