Holangita (cholangioma; from the Greek. chole - bile and angeion - vessel) - a tumor derived from epithelial intrahepatic bile ducts. There are cholangiomas benign and malignant.
Benign holangita (synonym: adenoma biliary tract, hamartoma biliary tract) occurs on the grounds of defects, mainly in children; can be single and multiple. Asymptomatic. Microscopically - randomly branching tubes are lined with a cylindrical or cubic epithelium with its own membrane separated layers of connective tissue. Benign cholangiomas difficult to differentiate from inflammatory growths of the epithelium of the bile ducts. The transition into a malignant form questionable.
Malignant holangita (synonym: carcinoma cholangiocellulare, carcinoma biliare) - a type of primary liver cancer (see Liver tumors). The etiology is not known. Of great importance previous cholangitis on the grounds of a bile stone disease and parasitic infestations (opisthorchiasis, schistosomiasis (snail fever, bilharzia). Macroscopic forms - massive cancer, nodular and diffuse cancer is indistinguishable from hepatoma. Microscopically malignant cholangiomas built-type adenocarcinoma. Glandular openings without its own membrane covered cylindrical or cubic cells. In stroma lot of mucus and acid mucopolysaccharides. Cholangiomas often combined with hepatoma. It is possible that cholangiomas and hepatoma have a single histogenesis and develop from primary hepatocytes. This view is based on the experimental study of liver tumors in rodents. Clinical course, diagnostics and treatment of cholangio are the same as in the hepatoma (see).