Chondrosarcoma

Chondrosarcoma (chondrosarcoma; from the Greek. chondros - cartilage + sarcoma) is a malignant tumor of the cartilaginous tissue. Is 10-15% of all primary malignant bone tumors. Chondrosarcoma common in men almost two times more often than women. Localization of chondrosarcoma various, but more often in the lower thigh and upper ends of the tibial bone less often in the bones of the pelvis, vertebrae, ribs, collarbones. Sometimes chondrosarcoma is developing on the ground benign tumor or non-neoplastic process - handsome, bone and cartilage exostosis.
Chondrosarcoma can reach large sizes, borders, it is not always clear; consistency photoelasticity, when a lot of mucus, decay or hemorrhage softer. Histological diagnosis difficult in cases with a large number of atypical, sometimes a giant multi-core cells (Fig. 1). If atypism expressed mild, there are difficulties in the differential diagnosis of chondrosarcoma and handsome (see). Base material tumors may undergo degenerative changes: a lot of mucus, necrosis, petrification. If the tumor is large plots myxomatosis tissues with his or stellate cells speak about chondroectodermal.
Chondrosarcoma is growing slowly; hematogenous metastases in the lungs, often in the liver, lymph nodes and other organs.
The main clinical symptom - long-existing possible to reveal certain tumor (Fig. 2). When viewed typically define a large tumor of the bone, located near the joints; movements may be difficult. The main method of detection and x - ray. At the Central chondrosarcoma is defined osteolytic lesion of the bone destruction with irregular shape, often with bone inclusions or petrifikatov.
Peripheral chondrosarcoma identified as dense tumor adjacent to the cortical layer of the bone, sometimes growing into it.
Surgical treatment; the scope of the operation depends on the tumor location. Radiation therapy is not effective.

Fig. 1. Chondrosarcoma. Polymorphism tumor cartilage cells.
Fig. 2. Chondrosarcoma the distal end of the femur.