Cocarboxilase (Cocarboxylasum; synonym: tiaminpirofosfat, Berolase and others) - the chemical structure pyrophosphoryl ether of vitamin B1. Cocarboxilase is kofermentom carboxylase regulating a number of reactions of metabolism of carbohydrates. Used for disorders of different origin, diabetic coma or pre-comatose state, circulatory failure, myocardial infarct, violations of heart rhythm, multiple sclerosis and other Injected intramuscularly in a dose of 0.05-1.0 g per day. Release capsules containing 0.05-0.1 g sterile powder that before applying dissolved in 1 ml of 0.5% solution novokaina. The capsules are stored at the temperature not more than 5 degrees.