Coli infection

If infection is a disease mainly of young children caused by pathogenic strains of Escherichia coli. At present we know more than 16 pathogenic serotypes of Escherichia coli: 0111 (B4), 055 (B5), 026 (B6), and others Established the etiological role of Escherichia coli in the occurrence of sepsis, peritonitis, anesthetic and other diseases.
To pathogenic strains of Escherichia coli most sensitive infants and young children, mainly preterm and weakened. Sources of infection are sick children. Infection occurs through contaminated hands staff, care items, toys, where E. coli keeps its activity to 130 days.
The incubation period for the coli infection 1-20, often 3-6 days. The disease usually begins acutely - with fever, vomiting, diarrhea and rapid development of toxemia.
Depending on the severity of the disease can first be recalled simple or toxic dyspepsia. Some children if infection develops gradually (within 2-4 weeks) and are manifested only in the unstable liquid stools, without toxicity. In the following days the condition worsens and develops toxicosis. For Kolya infection characterized by long-term (up to 15 days) temperature reaction, pale skin, developing due to vascular spasm. Cal watery, yellow, in some cases, with an orange hue and streaked with blood. Frequent stools (5 to 20 times or more per day) stubbornly kept (up to 2 weeks). As long the child may be vomiting (though not often 2-3 times a day).
During coli infection in children depends on the severity of the initial symptoms. Illness with acute onset ends in 3 weeks. C. case gradual beginning may be long, wavy, with recurrences, often from complications (otitis, Peoria and others). The newborn severe over - with severe morning sickness, vomiting, high fever, profuse diarrhea, dehydration. In infants along with severe forms of the disease are observed light, atypical and erased form, and in children older than 1 year, the disease may be the type of lung gastroenteritis. The severity of the disease depends on the type of pathogen. Most pathogenic strain is 0111.
When Troubleshooting coli infection in children of early age with external similarity with diseases such as toxic or simple dyspepsia, dysentery, crucial to bacteriological examination. Differential diagnosis of help especially if infection: long fever, vomiting, frequent diarrhea. The outcome depends on timeliness of early and correct treatment; mortality in Koli infection remains high, particularly among infants.
Treatment. In the presence of the toxic syndrome in infants need a break from feeding for 18 to 24 hours, the introduction of large amounts of fluid (isotonic solution of sodium chloride, ringer's solution, and glucose) -150-180 ml 11 kg of weight per day. In the subsequent careful dosed feeding breast milk, yogurt, rice broth (10 feedings 10 - 20 ml). The older children are recommended pureed vegetables, yogurt, acidophilus milk, cheese. Good detoxifying effect is obtained from intravenous infusion 25-30 ml of plasma. Be sure the application of b vitamins (B1 and B2 0,002-0, 005 g) and vitamin C 0.05 g 3 times a day.
Prescribe antibiotics neomitsinovoy number: kolimitsin 25 000 - 50 000 UNITS per 1 kg of weight per day 4 admission, polymyxin 100 000 IU per 1 kg of body weight per day in 3-4 reception, monomitsin 10 000-25 000 UNITS per 1 kg of weight per day in 2-3 reception. Antibiotic therapy should be performed within 7 days. In a relapse of the disease course repeat. Spend tonic and symptomatic therapy.
Prevention. The correct feeding, strict sanitary regime in institutions, early isolation of affected children. In children's establishment from which isolated sick child, disinfect. In children, communicate with patients, produce bacteriological examination of faeces. Being discharged from the hospital after clinical recovery and triple negative results of bacteriological research of a feces on pathogenic strains of Escherichia coli.