Cortisone (Cortisonum, Cortisonum aceticum; synonym: Cortone and others; list B) - hormone crust napochechnikov, belonging to the group of glucocorticoids (see Corticosteroids). Used in acute rheumatism, rheumatic, arthritic and infectious arthritis, some skin and eye diseases, acute leukemia, Addison disease, and others In the muscles of the daily dose can be introduced simultaneously, as cortisone of suspension slowly absorbed. When using inside in the early days of the daily dose divided into three parts on 0.05-0.1 g 2-3 times a day, then dose gradually reduced to 0.1 g a day before the onset of therapeutic effect, then reduced to 0.075-0.05 g per day. Treatment give 3 to 5 grams eye.
When Addison disease cortisone appoint 0.01-0.025 g / day. At the same time introducing desoxycorticosterone (see) to 0.001-0.005 g and sodium chloride to 10 g per day. Higher doses of cortisone: single - 0.15 g daily 0.3 g Cortisone can cause a number of side effects: swelling, increased blood pressure, hyperglycemia, exacerbation of ulcers stomach and duodenal ulcer. Contraindicated in pregnancy, ulcers stomach and duodenal ulcers, diabetes mellitus. Used under medical supervision. Method of production: powder, answers to 0.025 and 0.05 g and the vials of 5 and 10 ml of the suspension with the content of 25 mg cortisone in 1 ml
Cm. also Hormonotherapy.