Forecast in Crohn's disease

Spontaneous recovery in Crohn's disease is observed in 5.4% of cases (Crohn, 1949). The disease regardless of the method of treatment is chronically-recurrent nature, and the results of remote observations (from 5 to 15 years) frequency of relapse) varies from 50 to 78%. In the literature yet available summary statistical materials about the effectiveness of treatment of this disease.
Atwell and others (1965) details have traced the fate of 172 patients with a diagnosis of Crohn's disease in the period from 1939 to 1962 Freemasons were observed in 5-10 years. Just had 26 deaths, 20 of which were caused by the disease itself or operational intervention. Relapses met in the first four years after operation (in 50-60% of cases). It is essential that the recurrence rate did not depend on the localization, or on the prescription of disease, but to some extent correlated with the prevalence of pathological process. Relapse is particularly often met at a young age and in children. Authors prefer surgical, not conservative treatment. They recommend more likely to resort to resection of the affected regions, as the recurrence rate under these operations are relatively less and less often faced with the necessity of repeated interventions. The authors note the absence of explicit parallelism between radiological and clinical signs of revitalization of the disease. With long-term observation 25% of patients retained the ability to work and lead a normal life, but 50% gradually became invalids due to persistent pain, diarrhea, metabolic disorders, fistula formation, and so on, there is no doubt that in many cases complex therapy allows patients to return to work and gives them the opportunity for a long time to feel practically healthy people.