Chromatotherapy (from the Greek. chroma - color, kystis bubble, skopeo - examine, investigate) - functional-diagnostic method of research of the kidney and upper urinary tract based on allocation of Indigo Carmine from the upper urinary tract each kidney separately. For chromolithography using 0.2-0.4% solution of chemically pure Indigo Carmine, which injected (3-5 ml) or sometimes by intramuscular injection (15 ml). The Indigo Carmine is allocated from the blood mainly kidneys and liver and excreted mainly kanaltsevam apparatus of kidneys (88 - 92% substance). Chromolithography performed by cystoscopy (see)when we pass the urethra, adequate capacity of the bladder, there are no acute inflammatory processes in the urethra and male genital organs. Contraindications to chromolithography are: shock, collapse, principally, severe kidney failure and liver. The colour intensity of urine Indigo Carmine and term of its appearance in the bladder dependent on the functional state of the kidneys, its tubular apparatus, on the level of total and renal blood flow and urine output, total urinary tract and on the degree of urodynamics of the pelvis and ureter.
Some radiopaque substance, excreters kanaltsevam apparatus of kidneys and having the competitive effect of reducing the rate of blood clearance of Indigo Carmine and Vice versa. Therefore, the combination of chromolithography and excretory urography in one day may distort the results of these studies. To perform chromolithography need for 1-1.5 hours before the test to give to the patient to drink a glass of liquid (water, tea). The Indigo Carmine is injected into a vein only after insertion of the cystoscope into the bladder. The introduction of the cystoscope should be as painless, the bladder should be filled with warm liquid slowly (no more than 200-250 ml). Pain, low temperature of fluid, restretching bladder hinder the timely allocation of Indigo Carmine into the bladder. Injecting painkillers (morphine, pantopon, atropine) before homocysteinemia contraindicated, since they violate the dynamics of the urinary tract.
After examination of the bladder start monitoring the allocation of Indigo Carmine from ureter estuaries. Monitoring should start with the alleged healthy part because of the ureter mouth this side urine painted by Indigo Carmine, will come faster than on the side of the disease. When intravenous solution of Indigo Carmine with normal renal function and upper urinary tract it will stand out in the bladder for 3-5 minutes intensively painted blue stream, and in intramuscular - 8 - 15-th minute. Normal discoloration of urine Indigo Carmine matches the content in the urine of not less than 0.5 mg%. When monitoring allocation of Indigo Carmine need to monitor not only the time of its appearance in the bladder and degree coloration of the urine, frequency of contractions ureter estuaries and character throwing colored urine. For example, a contiguous selection colored urine from the mouth (as the smoke from the chimney") indicates the decrease in the tone of the upper urinary tract that may occur after removal of concrement of the ureter. Time allocation and the intensity of the coloration of urine Indigo Carmine distinguish chromolithography normal, low, and the lack of colourful functions. No urine output, dyed with Indigo Carmine, from the mouth of the ureter for 15 minutes indicates the oppression of the kidney or in violation of the passage of urine from the upper urinary tract (stone, stricture of the urethra, hydronephrosis and others). Because the Indigo Carmine allocated tubular epithelium, this colorful test indicates the nature of the excretory functions of the renal tubular apparatus of kidneys, and at the same time on the degree evacuation function of the upper urinary tract. When broken dynamics emptying of the pelvis and ureter the Indigo Carmine will not stand out in a timely manner to the bladder, even at normal function of the kidneys. It is often observed in the ureter stones. Timely allocation of Indigo Carmine in the bladder does not yet allow safe to assume that all of the renal parenchyma is functioning normally. Indigocarmina sample remains normal in the presence of kidney even a small section of a well-functioning parenchyma. This occurs by tumors of the kidneys, pyelonephritis. A great value of chromatotherapy has in diagnostics of acute diseases of abdominal organs (acute appendicitis and acute cholecystitis and other) with diseases of the kidney and upper urinary tract, manifested renal colic (stone pelvis, ureter, and others). Timely allocation of the intensely colored by Indigo Carmine urine from the ureter estuaries under normal results of the urine test allows to reject an acute disease of the kidney and upper urinary tract.