Digitalis

Foxglove
Foxglove red (Magenta) (Digitalis purpurea)

Foxglove (Digitalis) - herbaceous perennial plant. In medical practice, the following types: purple Foxglove (Digitalis purpurea), digitalis lanata (Digitalis lanata), digitalis rusty (Digitalis ferruginea) and Foxglove ciliated (Digitalis ciliata). Digitalis has specific cardiotonic effect, due to the presence of cardiac glycosides (see). Entering into effect of drugs naperstanki develops after a latent period. Glycosides naperstanki slowly excreted from the body, and therefore they have a cumulative effect, which is most pronounced in digitoksina and least - digoxin. Apply digitalis heart failure with symptoms of stagnation both the big and small circles of blood circulation, when Vice valves, tahiaritmiei forms of atrial arrhythmias, myocardial degeneration.
Therapeutic effectiveness digitalis expressed in increase cardiac output, decreased venous pressure, reduce the amount of circulating blood, acceleration of blood flow, reducing the size of the heart, blood pressure, increase lung capacity, increase diureza, the disappearance of oedema.
During treatment should be carefully monitored the cardiovascular system and the overall condition of patients. Consider also the possibility of individual hypersensitivity to drugs naperstanki. At occurrence of toxic effects (heart rhythm disorder, gastrointestinal and nervous breakdown) make a break in treatment. In severe cases, the use of potassium salts, novokainamid, camphor, atropine, ephedrine, magnesium sulfate and other means.
Treatment with drugs naperstanki are normally taken through nomination in the first 2-5 days maximum doses (to achieve the full therapeutic effect), then supporting dose, the level of which is determined by the discharge of glycosides. The introduction of non-digitalis preparations prior to throw in 10-20 ml 20-40% glucose solution.
Digitalis preparations are contraindicated in severe bradycardia, complete AV blockade, with frequent attacks of angina.
Foxglove preparations purple. A powder from leaves of digitalis (Purvis foliorum d) apply on 0.05-0.1 g 2-3 times a day inside and in the candlelight. The highest single dose of 0.1 g daily - 0,5, Digitoxin (Digitoxinum; synonym: Carditosin and others; the list a) - cardiac glycoside. Applied inside of 0.1-0.2 mg 2-3 times a day for 3-5 days, and then on 0.05-0.1 mg 1-2 times a day. The form of release: tablets 0.1 mg G and toxin (Gitoxinum; list a) - cardiac glycoside, several weaker digitoksina. Assign inside of 0.3-0.4 mg 2-3 times a day with subsequent dose of 0.1-0.2 mg the release Form: tablets to 0.2 mg Gitalin (Gitalenum; list B) - novogalenovy the drug. Applied inside for 10-15 drops 2-3 times a day; highest single dose of 0.75 ml, daily - 1,5 ml of Digipure (Digipurenum) - solution (70% alcohol) amount of treated digitalis glycosides. Appoint 10-15 drops 2-3 times a day or in the form of mikroklizm. Release form: bottles to 15 ml Kordigit (Cordigitum; list B): contains digitoxin, gitoksin and other digitalis glycosides. Convenient for long-term use, as it is less than digitoksin, cumulative effect. Assign inside for 1/2-1 tablet 2-4 times a day. Dosage form: tablets of 0.8 mg and candles 0.8 and 1.2 mg
The drug digitalis lanata differ from drugs naperstanki purple faster action and less cumulative effect. Zeland (Celanidum; synonym Isolanid; list a) - cardiac glycoside. Applied inside of 0.25-0.5 mg 2-3 times a day and in Vienna on 1-2 ml of 0.02% solution. Forms: tablets : 0.25 mg and ampoules to 1 ml of 0.02% solution. Digoxin (Digoxinum; synonym Cordioxyl; list a) - cardiac glycoside. Assign inside initially, 1 mg and then 0.25-0,125 mg / day; in the vein type of 1-2 ml 0, 025% solution. Forms: tablets : 0.25 mg, bottles, 15 ml ampoule 2 ml 0.025% solution. Abazin (Abicinum) is the sum of Hesse glycosides. The application, dosage and method of production are the same as for Zelanda. Lantose (Lantosidum; list B) - novogalenovy the drug. Assign inside of 10-20 drops 2-3 times a day. The highest single dose of 25 drops, daily - 75 drops. Divinized (Dilanisidum; list B) - novogalenovy the drug. Enter in the vein of 0.5-1 ml of the Form : ampoules to 1 ml of the Highest single dose of 1 ml, daily - 2 ml.
Foxglove preparations rusty. Digalen-neo (Digalen-neo; list B) - novogalenovy the drug. Assign inside of 5-15 drops 2-3 times a day. The highest single dose of 20 drops, daily - 60 drops; under the skin, respectively 1 and 3 ml release Form: bottles of 15 m and ampoules to 1 ml Taciturne (Satiturani): contains the sum of digitalis glycosides. Applied to the inside of 1-2 tablets 2-3 times a day. The form of release: tablets.
Foxglove preparations ciliate. Digicel (Digicilum) - novogalenovy the drug. Appoint 0.5-1 tablet 2-3 times a day. The form of release: tablets. Digitalen (Digicilenum; list b)- novogalenovy the drug. Injected under the skin or muscle of 0.5 - 1 ml 1-2 times a day. The release form: ampoules to 1 ml