Dyskinesia of large intestine

Under dyskinesia of large intestine should understand the violation of its motor function, which is connected with certain clinical symptomatology. An indispensable condition diagnosed dyskinesia of large intestine is the absence in the last postmortem changes. Dyskinesia may be the main and concomitant diseases.
Most often dyskinesia caused by disturbances in motor function of the large intestine caused by disorder of the nervous system. The latter is more often associated with organic diseases of the bowel (previous) or the occurrence of chronic psoriasis lesions (in the phase of exacerbation or remission) other digestive organs (stomach ulcer, chronic cholecystitis, pancreatitis, chronic gastritis). In the first variant is possible disruption of local (intestinal) nerve plexus (meisnerova and auerbaha), the second is increased tone of the parasympathetic nervous system, as well as serverelement influence. Dyskinesia of large intestine is also observed in endocrine diseases (thyrotoxicosis, diabetes) and for a number of toxic effects on the body, including some industrial poisons (a pair of lead). Less dyskinesia of large intestine may occur as if on their own, without any diseases of other organs. In such cases it must be assumed that in its development has a value of an inherited predisposition in the complex with negative environmental effects on the nervous system (private negative emotions, fatigue, disturbance regime of work and rest, food). The essence of disturbances in motor function of the colon at a dyskinesia is to strengthen the intensity and duration of the tonic contractions of the intestine (spasm), followed by a narrowing of the bowel (in the area spasm) and stop peristaltic waves. This mechanism is associated with increased excitability of local neural mechanisms. Along with this, in parallel (at another part of the intestine) may decrease in excitability of the nervous system that leads to depression intestinal motor entities and, accordingly, atopic status this section of the intestine. Usually dominates the first mechanism disturbances in motor function of the colon, and the symptoms caused spastic contractions segments of the intestine.
Basic to clinical dyskinesia are three symptoms: violation of the chair (constipation, sometimes alternating with diarrhea, flatulence, and abdominal pain. The chair is a once in 3-5 days, often in the form of "sheep Kala" (fragmented). Constipation can be replaced intermittent diarrhea, and the chair is not very frequent (1-3 times a day), quite abundant, and then again there comes a long delay of the chair. Flatulence is more or less pronounced, depending on this may be accompanied by a feeling of heaviness, swelling. These symptoms disappear after the discharge of gases. Abdominal pain are at a dyskinesia often cramping character. They may start gradually, rapidly increase, reaching significant intensity, in and of themselves weaken. After some time they are repeated again. Objective examination is sometimes possible to note bloating, spilled his tenderness to palpation, on the background of which probed spasticeski condensed large intestine (particularly sigmoid and transverse colon). For dyskinesia of large intestine is not clear phases (acute, remission, incomplete remission). The complex subjective symptoms may occur suddenly and for a short time (days) complete, and sometimes symptoms lasts a long time, resistant to treatment that doctors have to spend fruitless and a long investigation in search of organic disease.
If microscopic examination, except fragmented Kala, changes are not detected. Manifestations of psoriasis, particularly of the distal colon, you can monitor and, if rectoromanoscopy. While the proctoscope able to enter easily, often using only fanning the intestine air. On the background of normal or slightly irritated mucous membrane find spasmodic contraction of the colon. Syndrome dyskinesia may also be confirmed by an x-ray. Coprogram, sigmoidoscopy, aspiration biopsy and x-ray examination, which gives an opportunity to exclude organic diseases of the colon, have at diagnosis "dyskinesia of large intestine" more important than the methods of proving the violation of its motor function.