Endothelioma (endothelioma; synonym: angioedema) - option tumors of vascular origin, built of endothelium of blood (hemangioendothelioma) or lymph (lymphangiectasia) vessels.
The term "endothelioma" used very widely; this was attributed to cylindrem, hemangiopericytoma, glomus-angioma, chemodectoma, synonymy, mesothelioma, pigmented nevi and others as the exclusion of these tumors, the term came to be used much less frequently, as some authors have questioned the existence of tumors of the endothelium as well differentiated cells, Some authors regarded the term "endothelioma" even as "diagnosis of ignorance" (M. F. Glazunov). Recently, the existence of endothelial tumors is no doubt, however, the term is used with the notation "hemangio" or "libpango"characterizing the histogenesis of tumor more accurately. In the international nomenclature of tumors (who) hemangioendothelioma divided into benign (capillary angioma) and malignant.
Benign hemangioendothelioma occurs very often, especially in the skin, mostly on the face, and sometimes multiple, mainly in children. Dermatologists often mean capillary angioma as vascular nevus. Macroscopically benign endothelioma is a small sites are dark-pink, rising above the surface of the skin, often izyaslavs and bleeding. Microscopically, the tumor is composed of interlocking and anastomosis between the capillaries of different caliber, crowded with blood. Places marked areas proliferation of endothelial cells, mainly in the openings of the receptacles.
Benign lymphangiectasia differs from hemangioendothelioma the presence of papillary growths in the gaps gaps and a lack of red blood cells.
Masson (P. Masson) described the peculiar variant of intravascular hemangioendothelioma characterized by the growth in the spaces of large vessels (hemorrhoidal veins, veins of small pelvis, nasal polyps and other) branching of papillary ridges, covered by the endothelium that can perform all of the lumen of the vessel in the form of a blood clot.
Malignant hemangioendothelioma rare. They can occur in any organ and tissue, most often occur in the nose and throat. Sites are of the form pale pink color, thick consistency, in the context of homogeneous structures with hemorrhages. Have a pronounced local destroyuser growth, able to give metastases (mainly hematogenous, often in the lungs).

malignant hemangioendothelioma
Fig. 1. Malignant hemangioendothelioma.
malignant lymphangiectasia
Fig. 2. Malignant lymphangiectasia.

Histologically malignant hemangioendothelioma are characterized by the growth of atypical endothelial cells, sometimes with the formation of low differentiated vascular structures (Fig. 1), somewhere solid or alveolar structure. Cells are round, oval or slightly elongated with large, often pale or hyperchromic cores. In many cells mitoses. Meet giant multinucleated cells. Undifferentiated of hemangioendothelioma extremely difficult for the histological diagnosis and require special colors, in particular on argyrophile fiber.
Malignant lymphangiectasia extremely rare. May develop in breast few years after mastectomy. Microscopically are characterized by the presence of numerous deprived of erythrocytes cracks and cavities lined large atypical cells that make up places papillary patterns and solid fields (Fig. 2).
Treatment of endothelioma surgery followed by radiotherapy of malignant endothelium.