Eosinophilia in children

The number of eosinophils in children the rate is usually slightly higher than in adults (newborn to 8%, in the age from one year to five years - up to 5-6%).
Reactive (secondary) eosinophilia - increased number of eosinophils (to 10-15%) at normal or slightly increased amounts of leukocytes - children accompanied by the same disease as adults, but more common in a number of allergic conditions. Due to the high permeability of the gastro-intestinal barrier for young child (and in some constitutional peculiarities of metabolism and in older children) enteral sensitization by travaillerai plays a particularly important rol. Eosinophilia in children is the companion of a number of allergic conditions and symptoms: expressed dermal manifestations of exudative diathesis, asthmatic bronchitis and bronchial asthma, urticaria, and so on, it is Possible that eosinophilia observed in such skin lesions, as neurodermit, swelling Kwinke, desquamative scarlatinopodobnaya erythema, syndrome Stevens-Johnson, some forms of medicine and others, connected with the formation in the skin of large quantities of histamine and gistaminopodobnykh substances to which eosinophils are observed phenomena tropism. Eosinophilia - permanent symptom the number of toxic and allergic akzente, including those caused by medication (calomel, sulfa drugs, penicillin, streptomycin, preparations of liver, serum, and other). Eosinophilia is peculiar rare congenital diseases - family pigmented skin Bloch - Sulzberger, the Aldrich syndrome and a number of endocrinopathy (acromegaly" syndrome Simmonds and gipokortitsizm).
From the second year of life become important eosinophilic reactions in the development of infectious process (scarlet fever, tuberculosis hepatolienal systems l, gonococcal infection), and in the period of recovery from hepatitis, lobar pneumonia, and so on, For some "big collagen diseases" and a number of infectious-allergic conditions (periarteritis nodosa, nonspecific polyarthritis, septic endocardit, a hemorrhagic vasculitis and others) can be accompanied by eosinophilia.
Reactive eosinophilia in children have parasitic etiology (the number of worms, sometimes giardiasis), especially when tissue localization parasites.
Large eosinophilia. Along with reasonable eosinophilia in children more sharply than in adults, expressed tendency to growth of a very high eozinofilia (more than 15-20% with a significant leukocytosis). In the group of large eozinofilia blood comes with a number of diseases with unclear etiology. This so-called infectious eosinophiles (I. A. Cashiers, 1958), characterized by acute or subacute onset, undulating fever, polyarthralgia, Qatar nasopharynx, diarrhoeal disorders, hepatosplenomegaly, giperlakotsitos with high eosinophilia no signs of violation of maturation of eosinophils in the bone marrow. Described tropical eosinophilia, which have long fever, increasing respiratory disorders asthma nature, persistent dry cough, defined radiographically seal roots and infiltration in the lungs, giperlakotsitos and hypereosinophilia (80%). Most researchers recognize parasitic (filarial) etiology of this disease.
Other causes large eozinofilia in children are the same as in adults.
System (primary) eosinophilia diseases of blood-forming organs in children is very rare (chlamydia, eosinophilic leukemia).
Constitutional and birth family eosinophilia occur occasionally in healthy children.