Erythromelalgia (synonym disease Mitchell) is a disease of the blood vessels (angiographers), based on the violation of peripheral vasomotor reflexes, leading to paroxysmal dramatic expansion of the arteries and veins of the extremities. Often erythromelalgia observed in those of syringomyelia, myelitis, endarteritis. More common in men. Apparent sudden or gradually developing bouts of acute pains in distal departments of the feet and hands.
Pains are burning, intolerable character. The affected area limbs reddens, swells, there is a sudden sweating in the area of edema, increased skin temperature, Palpation of the skin and subcutaneous tissue disorders very painful. Peripheral arteries and veins in the time of the attack tense, heavily pulsate. The attack lasts from several hours to several days.
In the place of the former edema may develop a rash, peeling skin, nail changes. Defeat is often symmetrical character. Pain can occur more frequently in hot weather, walking, provoked sdavlennoy and warm limbs, reduced cooling and the rise of feet or hands up.
Treatment of erythromelalgia: during and between attacks appointed sossoudossoujiwate drugs (ephedrine and others), tonic (caffeine). Justified the use of ascorbic acid, rutin, calcium, aspirin. To prevent attack should avoid overheating, it is recommended to wear light shoes. In severe cases is the excision of sympathetic nodes.

Erythromelalgia (erythromelalgia; from the Greek. erythros red, melos - limb and algos - pain; synonym: disease Mitchell, morbus Weir-Mitchell, oedema cutis circumscriptum dolorosum) is a disorder of the autonomic nervous system, characterized by the following symptoms: 1) the pain that appears usually in the evening pristupoobrazna in the lower extremities, often starting with the big toe (pain is usually burning); 2) swelling, pinkish colors, it is very red swollen veins and ripple arteries; swollen skin sharply painful; 3) the temperature increases by 2-4 degrees and in the field swollen area propagating in further to the entire limb; 4) various trophic disturbances.
Having started with the big toe of one foot, the disease usually generalizada, applies to the other leg, hands, nose, ears, sometimes the breast (women). Erythromelalgia attacks of pain and trophic disorders can achieve great intensity, accompanied giperbolicheskie phenomena that interfere with walking, and sometimes make it impossible. Warm feet increases the pain, cooling reduces. During the attack the skin on the foot is covered later, Vienna expanded.
The pathogenesis of the disease is not clear. Still not established, at what level of the nervous system are affected vasomotor devices and whether the occurrence of the disease excitement vasodilator devices or from braking vasoconstrictor. In the basis of the disease can lie organic changes in the cells back the horns of the spinal cord in the back counterfoils, and in the nerve trunks tibial nerve in the leg and muscle-skin on his shoulder. In addition, in some cases, they found suffering cerebral napochechnikov layer and a sharp increase in chromaffin cells in them and sympathetic nodes.
Treatment of erythromelalgia insufficiently developed. Recommended quinine, ephedrine, caffeine, ascorbic and glutamic acid. Produced ganglionectomy LII-LIV sympathetic nodes.