Pages: 1 2

Examination of drug intoxication

In the classification side effects of medicines are considered different in origin complications: allergic, toxic and metabolic, infectious, and neurogenic caused by the cessation of drug administration (withdrawal symptoms or symptoms).
Acute reaction to the use of medicinal substance - Allergy - occurs selectively to one or group of drugs. It should also be borne in mind that when undiagnosed sensitization of the body receiving the medication could be accompanied by unexpected functional disorders and even lead to death. Sensitisation may cause applied themselves are non-toxic substances (such as penicillin, streptomycin, salicylates, and other).
For the prevention of drug allergic conditions physician must carefully collect and analyze historical information that is relevant to a specific patient, paying particular attention to what the medicinal product, used in the past caused him acute painful disorders.
A forensic expert to prove the occurrence of allergic States should study the investigative materials and medical documents, producing inpatient or outpatient examination of the injured, and when death is the study of the corpse with the use of forensic chemical, microscopic, bacteriological and other laboratory techniques. The conclusion about the emergence of severe allergic reactions to the medicinal product should be based only on the study of the aggregate of all data collected.
Medical documents (originals) diagnostic value in the definition of drug Allergy have anamnestic information reflected in the maps of out-patient or in-patient, as well as describing the picture is sharp, the body's response to drug therapy.
As is known, the manifestation of acute forms of drug Allergy can be expressed in the development of anaphylactic shock, angioneuroticeski swelling, bronchial asthma and acute hemolytic anemia; these conditions may occur separately or in combinations. Recognition called acute forms of drug Allergy is based on the analysis of aggregate data of clinical, morphological signs and laboratory findings.
When non-fatal cases of drug Allergy may be necessary expertise of health disorders as the effects of allergies that almost obliges forensic medical expert to determine the severity of injury in accordance with the applicable rules. If allergic condition has resulted in death, the expert causation should be based on the clinical picture and examination of the body with the obligatory laboratory (forensic chemical, microscopic, bacteriological and other).
Self-importance poisoning medicinal substances arising in everyday life. The reasons of such poisoning is most often: the ingestion of drugs for external use, dose, drug use, is not suitable for the underlying disease, use of medications that have become unusable, careless or incorrect application of funds, similar in external properties (color, odor and others), a simultaneous intake of alcoholic beverages. All these circumstances may be the subject of investigation. Besides the mentioned circumstances under which a possible domestic drug intoxication, must remember forensic medical expert in the study of bodies of persons who died suddenly.
When drug intoxication, occurring in the home, the examiner should bear in mind the possibility of their deliberate origin. It is established investigative and judicial authorities on the basis of all collected materials, in which a certain evidential importance is attached to the results of the inspection of the scene, data forensic medical study of the corpse and forensic chemical examination, the objects seized at the scene and autopsy of the corpse. This diagnostic significance should be attached to the quantitative indicators, identified by laboratory analysis.

Checklist
1. What are the basic rules of storage of medicines in General and potent in particular.
2. Describe the main provisions of prescribing and dispensing drugs to the patient.
3. What are the main provisions that govern the medical staff at the infusion and transfusion.