Fibroblasts subendocardialnah

Fibroblasts subendocardialnah - congenital disease of the endocardium and subendocardialnah layers of the myocardium, characterized by hyperplasia of elastic and collagen tissue, increasing size of the heart. Fibroblasts subendocardialnah often combined with malformations of the heart and blood vessels.
Clinically, there are 3 forms course: lightning, acute and chronic.
With lightning-fast form in children during the first days or weeks of life all of a sudden shortness of breath, cyanosis, cough, rapidly growing phenomenon of heart failure. Radiographically is determined by the increase of the size of the heart and barely noticed his breathing. On electrocardiogram - negative the T wave, high, and P wave and in-depth Q. Death occurs within a few hours or days from the onset of the disease.
The acute form subendocardialnah fibroelastosis more frequently observed among children 3-6 months of age. The clinical picture as with fulminant form. When events progressive heart failure child dies after 2-3 weeks from the beginning of the illness.
Chronic form subendocardialnah fibroelastosis observed in children of older age. The disease develops slowly over months or years. Appear fainting, pallor, tachycardia, seizures, painful cough, shortness of breath. Increase the size of the heart, noises in the heart are missing or poorly expressed. Progressively increases the blood circulation, increases significantly the liver.
Diagnostics subendocardialnah fibroelastosis difficult. To differentiate subendocardialnah fibroblasts should pericarditis, pneumonia, acute myocarditis and heart disease. The prognosis is unfavorable.
The treatment is ineffective. In heart failure, on the recommendation of a doctor appointed drugs digitalisa, prednisolone. Shown surgery - injection sterile talc and magnesium in pericardial bag to stimulate the development of new blood vessels and improve blood supply to the myocardium. If started early, systematic treatment subendocardialnah fibroelastosis is sometimes possible to stop the process and even get back its development.