Hepatitis is liver damage different nature. On the clinical course of hepatitis divided into acute and chronic.
For proper treatment and prevention of disease apply the division of hepatitis through etiological principle. Infectious hepatitis: a) primary - epidemic hepatitis a, b) secondary - for persistent septic endocarditis, pneumonia, syphilis, malaria, intestinal infections and intoxications. Toxic hepatitis - drug (chlorpromazine, salvarsan, chloroform, Tofan, PAS and others), industrial, food, household poisonings. Exchange hepatitis, disorders of metabolism related to insufficient consumption of protein, vitamins and other Toxic-allergic hepatitis when using certain drugs (penicillin, streptomycin , and others), by blood transfusion. Along with the etiologic classification principle exists and clinico-morphological classification of hepatitis. This is caused by the fact that the same etiological factor can cause different morphological types of hepatitis. By morphological principle hepatitis divided into diffuse parenchymal, diffuse mesenchymal and alopecia.
Diffuse parenchymal hepatitis is characterized by lesions of the liver cells, combined with certain clinical symptoms: weakness, lack of appetite, pain in the right hypochondrium, jaundice. Affected also the reticulo-endothelial tissue liver and spleen, intrahepatic bile ducts, the serous membrane liver (perihepatitis). Objectively find liver enlargement and tenderness on palpation, enlargement of the spleen and the perversion of the functional liver samples (See Liver, functional diagnostics). At the end of hepatic beams can occur massive necrosis of the liver (see Liver, massive necrosis). The emergence of less significant necrosis leads to the development of chronic hepatitis, often ending with cirrhosis of the liver (see). Sometimes acute diffuse parenchymal hepatitis clinically poorly defined, and reliable diagnosis is possible only when using laboratory studies (see Liver, functional diagnostics). In diagnosis may also help history (epidemic, professional). Occult hepatitis is not always strengths.- They may be the beginning of a chronic or recurrent HCV outcome in cirrhosis. With proper treatment, even long-existing hepatitis can result in complete recovery.
Diffuse mesenchymal hepatitis is an interstitial inflammatory process without the participation or with minor participation parenchyma. This form of hepatitis may occur in malaria, persistent septic endocarditis, brucellosis and other low current chronic infections. Clinical manifestations the disease is small and is caused by the electoral defeat of the reticuloendothelial system. Most often, there is a modest increase in liver and spleen, dysproteinemia, lymph nodes and bone marrow.
Focal hepatitis often develops tuberculosis, syphilis, brucellosis, sarcoidosis , and etc. the Diagnosis is very difficult due to the absence of detectable clinical signs. In the decay and suppuration foci clinical picture is no different than when suppurative the process of liver of any etiology (fever, leukocytosis).
The diagnosis of hepatitis expressed in cases not difficult. Reference point are: history, the presence of jaundice, enlarged liver, spleen, data of laboratory researches.
The treatment of diffuse hepatitis-see Hepatitis epidemic. In the treatment of focal hepatitis is necessary to consider the etiological factor.
Prevention - the need to prevent infectious diseases and intoxication.