Method of radioisotope gepatoenteralna

Method of radioisotope gepatoenteralna based on the fact that hepatocytes selectively absorb Bengal rose labelled J131, and reticuloendothelial cells accumulate from the colloidal solution of radioactive gold (Au198) or chromium (Cr61). Using radiometric unit - scanner that touches notes incoming pulses, one can study the distribution of radioactive substances accumulated in the tissues, getting in fact stenograficheskii image of authority.
Using labeled Bengal rose (at a dose of 200 mcg) to receive stenogrammu liver and 30-60 minutes after the introduction of substances - radikalisierung and monitor the withdrawal of the radioisotope in the intestines. After the introduction Au198 get stenogramma not only the liver, and spleen. For scanning spleen used radioactive chromium.
Stenogramma liver healthy person corresponds to normal topography of the authority. Dense and uniform shading indicates uniform and fully functional state of hepatocytes (Fig. 57). In severe forms of Botkin infectious hepatitis and chronic hepatitis significant diffuse attenuation hatch (Fig. 58). With postnecrotic cirrhosis on stenogramme seen pockets of dense hatch, corresponding to the major centers of regeneration, and areas of significant dilution corresponding fields of Andrey. In portal, and biliary cirrhosis shading diffuse thinning (Fig. 59)and on the periphery of the body, the process is more pronounced. Local changes of the liver are identified at stenogramma as defects of radioactivity - white fields. When single-Echinococcus, cysts and hemangiomas out of defect of radioactivity is fixed normal function of the liver tissue. Primary cancer of the liver and alveolar hydatid cyst, along with a focal depositions, signs diffuse liver dysfunction.

Fig. 57. Gepatoenteralna healthy person (by A. S. Loginov).
Explanation in the text.
Fig. 58. Gepatoenteralna in chronic hepatitis (by A. S. Loginov). Explanation in the text.
Fig. 59. Gepatoenteralna with biliary cirrhosis (by A. S. Loginov).
Explanation in the text.

The highest value of radioisotope gepatoenteralna has to recognize focal diseases of the liver, abscesses, Echinococcus, tumors, unavailable endoscopy; it can be successfully applied to determine the presence of metastases in the liver, with various malignant diseases of other organs.
According to the observations Wagner with TCS. (1961), focal lesions of the liver with a diameter of less than 1.7 cm on stenogramme not detected; foci 2.5 cm in diameter are determined only upon their surface location.
The resolution of the method increases significantly when using color scanning, where different level of activity in the parts of the body indicated by the strokes of different color, or tsifropechatayuschee system, where the level of activity is passed in a numeric expression. In recent years developed a number of methods of mathematical processing of scenogram (A. S. Loginov, etc., 1970).