Hypertensive disease, its prevention

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The modern pace of life, urbanization, tennisace and production automation, undoubtedly, created have increased stress on the nervous and cardiovascular system. Not less load in the course of employment accounted for by other systems management and maintenance of the body. These pressures could be compensated and overcome using adaptive mechanisms arising in the process of the organism, if the people themselves are not created additional stress underlying the development of various diseases, including hypertension and hypertensive disease.
Various risk factors and stress influence, especially the so-called verbal stress, so strong that quickly cause stress functions of systems management body, involve primarily the most reactive of the nervous system in which the collision of the excitatory and inhibitory processes in brain cortex occurs neurosis. It should be emphasized that despite the use of alcohol, Smoking, noise and other impacts negatively influence of extraordinary combination of two or more stimuli that can cause neurosis underlying the development and clinical manifestations of hypertensive disease.
Stage I of the disease and there is not that other, as vascular neurosis, acquiring progressive course. Over time, this neurosis under the influence of adverse effects is gaining momentum in its development, and thus against the background of the nervous component included new, pathogenesis, such as atherosclerosis of main arteries, disorders of the functions of the renin hypertensive system and metabolic disorders, especially those that lead to obesity, reduced tolerance (endurance) to carbohydrates, the development of diabetes, etc. Each of these pathological processes aggravates the clinical course of hypertension.
The largest Soviet cardiologist A. L. Myasnikov [1960] noted that there was no pressure and no atherosclerosis as a separate disease, and there is a common disease that develops in some individuals as hypertension, others as atherosclerosis, and most often both painful process simultaneously or sequentially. Therefore, we must bear in mind that the progressive development of atherosclerotic process affects the course of hypertension and, on the contrary, intensive course of arterial hypertension affects atherosclerotic process, especially when it affects the coronary and cerebral arteries. High blood pressure constantly increases the workload of the heart, often complicates the clinical course of ischemic heart disease. Hypertensive crisis can often be the harbinger of myocardial infarction, so the presence of these two diseases requires careful attention as the doctor and the patient, especially in terms of observance of a mode of work and rest.
However, hypertension may long time to take place without major changes in the heart, and in this case it is not negatively affect the General state of the patient, his health and activity.
A. L. Myasnikov pointed out that the increase in blood pressure caused by a primary violation of cortical and subcortical vascular system regulation in the disorders of the higher nervous activity with its subsequent involvement in the pathologic mechanism hormonal factors.
Along with the violation of cortical neurodynamics, i.e. complex regulating the activities of the processes, and with the disorder of the function of the autonomic Pressor centers that control the tone of blood vessels, essential acquire changes neurohumoral regulation (constancy of the internal environment of an organism). The disequilibrium between adrenergic and cholinergic substances arising from the tone of sympathetic-adrenal system, leads to the violation of local and General blood flow, as well as to the development of changes in the structure and function of the vascular wall, first of all vessels in the kidneys. Ischemia renal parenchymal causes the dysfunction of the renin hypertensive system, increased production of renin and development pressure (vasoconstrictor) effect. In the tonus of vessels greater role for the hormones of the adrenal glands, and first of all the aldosterone, adrenaline and noradrenaline.