Gonococcus and its properties

The name "gonorrhoea" means "expiration seed," as the ancient doctors thought pus released during gonorrhea, there is nothing like expiring seed. Only after the opening of Naser (1879), became known, that the causative agent of gonorrhea is a particular kind of diplomacy, which received the name of gonococci (Fig. 63).
Painted drug under the microscope gonococcus has the shape of a coffee bean and is paired with another gonococcus. Both of gonococci its broad, slightly concave sides facing each other and almost touching; convex side of them facing outwards. During the reproduction of each pair is split into two new pairs in the direction perpendicular to the gap between them. Group gonococci are part of intracellular in leukocytes, which they phagocytic, part - outside the cells, part of the same are located on the surface slomannyh epithelial cells.
Gonococcus easily painted main aniline dyes (methylene blue, Magenta); with special gram stain gonococcus becomes more color (i.e. at colouring by Magenta - red, while stainable bacteria are purple).
Gonococcus outside the body is very unstable microbe. He quickly dies at drying secret; only in humid environments (wet linen, warm water) gonococcus can remain viable for up to 24 h and serve as a source of infection.
Gonococcus very sensitive to temperature change. Optimum temperature for growth of gonococci outside the body 35-38 degrees. At temperatures below 30 degrees, the growth of colonies stops below 18 degrees they die. When exposed to a temperature 40 degrees gonococcus outside the body dies after 6-8 hours
Gonococcus not form a soluble toxins, but when death and the collapse of gonococci released their endotoxins, which cause inflammation of the mucous membranes and cause a devastating effect gonokokkov on the fabric.
Gonococcus able to penetrate through the intact epithelial mucous membranes, causing an inflammatory reaction in the surrounding tissues. A favorite place for the development of gonococci are mucous membranes, lined with cylindrical and transitional epithelium (urethra, cervical canal, the body of the uterus, tubes, rectum). However, gonococcus may develop in the germinal epithelium of the epithelium of the follicles, on the peritoneum, the synovial membranes joint, tendon sheaths, mucous bags, the conjunctiva, the endocardium, submucosal connective tissue. The defeat of fiber in gonorrhea is rare.
Flat multilayer epithelium vagina adults, especially nagaragawa women affected rarely and only when pregnancy and in the period of menopause due to special conditions (swelling, dispersing and desquamation of the epithelium) predisposition to the disease increases significantly. Gentle squamous epithelium of the vulva and vagina children and girls is a favorable place of localization of gonorrheal infection.
Immunity against gonorrhea does not exist, so it is possible reinfection.