Granulation tissue

Granulation tissue (synonym: granulation, granular tissue)- young connective tissue, formed in the healing of wounds and inflammatory lesions. Granulation tissue is usually bright red, juicy, wibehouse on the surface of the capillaries give it a grainy appearance, hence its name.
Microscopically granulation tissue is composed of newly formed blood capillaries and a large number of cells (histiocytes, Poliplast, polymorphonuclear leukocytes, lymphoid, plasma cells, and others). Granulation tissue Matures with the formation of connective tissue fibers that ends with scar formation. Fast maturing granulation tissue depends on the age of the patient, the power status of the neuroendocrine system, metabolism. In adverse conditions (hypovitaminosis, depletion, the presence of foreign bodies, and so on) ripening of granulation tissue are extended. Granulation tissue gains grayish color, dry type, the surface becomes smooth, bleeding. Excessive development of granulation tissue or delay of its maturity you need to install the cause of these phenomena and only then to apply local or General treatment (see the Wound, injury). To determine the cause of the delay maturation of granulation tissue, as well as to differentiate this tissue tumors should resort to biopsy (see). Cm. also, Inflammation, Granuloma, Regeneration (pathology), connective tissue.