The hemagglutination

The hemagglutination - bonding and precipitation of red blood cells. Distinguish between active and passive hemagglutination.
Active hemagglutination happens when you step on the red cell antibodies, lectins (substances derived from plants)and viruses (influenza and other - Viruses neutralized antiviral sera, lose their ability to cause hemagglutination, so the reaction of the active haemagglutination is used to determine the titer of virus titer neutralizing antibodies, as well as to determine the nature of the investigated virus. Active hemagglutination widely used to determine group membership - blood (see blood Group).
Passive hemagglutination occurs under the influence of serumspecific to the antigenadsorbed on red blood cells. For the given reaction passive haemagglutination (DSA) requires a small amount of antigen (see) and antibodies. The adsorption of antigen to produce red blood cells treated with tannin.
If the serum agglutinate erythrocytes, they strewn almost all of the bottom of a test tube or wells. In case of negative result of the research, the red blood cells are collected in a CD.
To check the specificity of the reaction using the reaction of haemagglutination inhibition (RTG): in pre emaciated with free antigen serum add sensitized red blood cells. The phenomenon passive haemagglutination is widely used in clinical and laboratory practice. Cm. also Agglutination, Virological tests, Serological studies.