Chordoma is a rare dizembriogeneza tumor arising from the remnants of the spinal strings (chorda dorsalis).
Chordoma is localized in the skull (Blumenbach scat), the sacrum and other parts of the spine, often (ectopic form) in the Turkish saddle, nasopharynx, sinus cavity, pelvis. Can occur at any age, mostly young, most men.
A tumor is a bulging, usually small, soft consistency, translucent appearance in the section, frequently lobed structure. Microscopically chordoma consists of the Islands largest polygon light vakuolyarnyi cells with clear boundaries and small, often pinnatifida, nuclei (Fig.). The Islands are separated tender fibrous layers stroma, often galinadiamond. Between cells are found slit-like cavity. In the cytoplasm of cells contain glycogen and lipids. Malignant chordoma encountered much less benign, are ativismo cells. Cells are commonly smaller. They get round or oval shape, lose usercountry view, which is sometimes very difficult to microscopic diagnosis.
Benign chordoma.
Clinical manifestations chordoma depend on its location. In the skull chordoma may be accompanied by symptoms of stem compression of the brain, spine chordoma is able to compress the spinal cord or cause dysfunction of pelvic organs. Malignant chordoma is characterized by rapid growth, destruction of surrounding tissues, can metastasize to lymph nodes, lungs, liver, etc.
The surgical treatment in combination with radiation therapy.