Chronic leukemias in children

Chronic leukemias in children are much less acute. Chronic forms of leukemia in children almost never occur; chronic myelogenous leukemia is a rare, relatively more likely to have to see the leukemia and subleikemical form of chronic myeloid leukemia and less frequently - leikemicakie. In children, their course and symptoms are the same as in adults.
Treatment of chronic myelogenous leukemia. The basic installation of treatment of chronic myelogenous leukemia in children are the same as in adults. However, even in older children pathological process is almost never enough compensated and therefore not always possible to be limited to only one restorative treatment, even if the child feels quite well.
A sick child when the discovery of leukemia is subject to compulsory hospitalization for detailed clinical examination and treatment. It should ensure the correct mode of life, proper nutrition, rich in vitamins; eliminate the possibility of any physical and mental fatigue. If possible, it is necessary to refrain from active therapy and limited restorative treatment.
Testimony to the appointment of a specific treatment for chronic myeloid leukemia have to be the violation of child's health, increase in the number of cells more than 20-25 thousand, a significant enlargement of the spleen, the growth anemic phenomena and a significant acceleration ROHE. Even in the absence of myeloblasts in the peripheral blood of these symptoms indicate instability practical relative well-being of the child, on the need of treatment.
From chemotherapy drugs can be recommended mielosan (mileran) - 0.1 mg per 1 kg of body weight per day in 2-3 reception, Doan - 0.15 mg per 1 kg of body weight 2-3 times per week, nowambien - intravenous 0.15 mg per 1 kg of body weight. From the funds of radiation therapy shown radioactive phosphorous (P32) and radiotherapy on the background of intravenous 30-60 ml erythrocyte mass or 50-120 ml whole blood. At elevated temperatures prescribe antibiotics. Inside: calcium chloride or calcium gluconate, ascorbic acid, vitamins P (rutin and others), B6 (as indicated) and other Drugs of the liver (campolon, Antianemic, extract the liver and other), as well as vitamin B12 noticeable impact on anemia with leukemia do not have; sometimes it is possible to note a General tonic effect.
In remission child can lead normal for his age way of life, to visit a kindergarten, school and so on, but should not overwork. During this period, it is desirable purpose of ascorbic acid and other vitamins, calcium and iron. With a slight worsening shown briefly supportive treatment malosana or dapnom. At the first sign of a more sharp aggravation of the process (high temperature, the appearance of undifferentiated cells in peripheral blood and so on) shows the assignment of the 6-mercaptopurine, prednisone and other corticosteroids.
In chronic forms of myelogenous leukemia can be assigned and urethane (0,5-0,75 g 3-4 times a day); however, the majority of children it causes vomiting, decreased appetite, and often depressed mood. Cm. also Retikulez.