Along with hormonal treatment of disorders of the menstrual function and menopause, in recent years are the spread of non-hormonal methods impacts, based on theoretical assumptions about neuro-hormonal nature of regulation of the reproductive function of women.
In this monograph covers the foundations of modern views on the reproductive function of women, establishing and violations with particular focus on the role of the peripheral and Central (hypothalamic) mechanisms (Chapter 1). Further outlines the clinical features and peculiarities of diagnostics of the menstrual function and their classification in the light of the definitions of those diseases that may use a variety of methods of hormonal therapy (chapters 2, 3).
In the following chapters (4, 5, 6, 7) understand the experimental data, the method of use on patients, the efficiency of the use of such methods as indirect stimulation of the hypothalamus-pituitary area, longitudinal diathermy brain, impacts on the upper cervical sympathetic ganglia, electrical stimulation of the cervix when amenorea, violations of ovulation, dysfunctional uterine bleeding, infertility in women in different age periods.
The final Chapter considers the questions of pathogenesis of climacteric neurosis, role and place of various medical and physiotherapeutic funds in its treatment.
The edition is intended for obstetrician-gynecologists, endocrinologists, dermatovenereologists.
The monograph contains 40 drawings, 12 tables, bibliography - 223 names.
Table of CONTENTS
Introduction
Chapter 1. Regulation of menstrual function
Chapter 2. Clinical signs of the phases of the menstrual cycle
Chapter 3. On the classification of menstrual disorders and their clinical manifestation
Chapter 4. Indirect stimulation of the hypothalamus-pituitary region
Chapter 5. Longitudinal diathermy head and inegalitarian by Scherbak in the treatment of dysfunctional uterine bleeding
Chapter 6. The impact on the area of the upper cervical sympathetic ganglia
Chapter 7. Impact on the cervix with dysfunctional uterine bleeding
Chapter 8. Impact on the cervix pathology, not involving uterine bleeding
Chapter 9. Climacteric neurosis and ways of its non-hormonal treatment
Conclusion
In our monograph were shown the opportunities clinicians have now to provide non-hormonal influences purposeful influence on the process of ovulation or violated higher gipotalamicheski vegetative functions.
The question arises: are exhausted there opportunities in this direction? Should be answered in the negative, as in recent years in numerous experiments was shown a role negiotiations entities in the implementation of menstrual function. These include the so-called ancient brain structure and reticular formation. It is known that exposure attached to almond kernels, rhinencephalon-limbic system, affect the estrous cycles until it is time to stop deleting nuclei; almond-shaped complex stimulates the secretion of both FSH and LH; off olfactory stimuli by narcotizirutego of nasal mucous membrane leads to a false pregnancy, and the removal of the olfactory bulbs of the brain leads the rats to atrophy of the ovaries; similar reaction can be obtained by influencing the hippocampus.
The most marked effect on the endocrine function provides the reticular formation. In particular, the oppression of the reticular formation prevents ovulation, and infantile animals leads to delay the onset of puberty.
Research of influence of a number of neurotropic drugs, the point of application which are reticular formation, or the ancient structures of the brain showed that they can have a significant impact on the sexual cycle of animals and menstrual function of the person. In particular, found blocking effect of chlorpromazine on ovulation and, on the contrary, the stimulating effect of amphetamine. These facts we see ample opportunity for research in terms of finding and experimental and clinical trials of a variety of neurotropic drugs affecting ovulation.
Whether it is expedient for violations of ovulation to use any of the listed in this book ways? Apparently not, and this denial can be based on the work of Masonic lodges of the Crimean showed that ovulation disorders can develop as a result of primary disturbances in the hypothalamic-pituitary system, and as a result of the primary changes in the effector organs (ovaries, uterus). This fact is the assumption that when the Central mechanism of ovulation disorder most reasonable would be the use of indirect stimulation of the hypothalamus-pituitary area, the use of neurotropic drugs, blockade of the upper cervical sympathetic ganglia, diathermy brain, and at the primary changes in the sex organs are the stimulation of the receptors of the cervix in a variety of ways, impacts on areola area.
Occurs at last, and the following question: whether it is expedient to develop various non-hormonal methods of influence on the process of ovulation in light of the success of biochemistry, gave currently in the hands of the artificial hormone-releasing factors pituitary hormones with high effectiveness of their use, which clearly showed the VII international Congress of obstetricians and gynecologists, which took place in 1973 in Moscow?
We believe that whatever a high degree of efficiency neither had mentioned substances, ultimately, their use is substitution therapy, although higher its views in comparison with application of ovarian hormones. The use of non-hormonal influences designed for stimulation (or corrections) functions without making outside hormonal substances, and success in these types of therapy can truly explain the regulatory influence of the non-hormonal methods for neuro-endocrine system.
At the same time it should be stressed that the use of a nonhormonal funds regulation ovulation does not exclude the use of hormonal drugs. In some cases, the combined effect of hormones and neuroreflectory ways improves outcomes. In particular, this was clearly demonstrated in women with anovulatory cycles, when separate application horohorina and stimulation of the cervix was in respect of pregnancy is less effective than the combined use of these two methods.
Recommended literature
Becker S. M. Pathology of pregnancy. Ed. 3-E. L., "Medicine", 34 L.
The book is a complete guide to the issues of pregnancy pathology. In 1965 the first edition was awarded the prize to them. C. F. Snegireva. It contains information about all currently known complications of pregnancy, highlights their incidence and etiology described clinical forms, methods of prevention and treatment. Of particular interest are the chapters on cardiovascular pathology and infectious diseases in pregnancy and the combination of collagen and hereditary diseases and pregnancy.
The present publication is supplemented by the section "the Tactics of the complicated delivery", introduced the latest data on late toxaemia of pregnancy, incomplete pregnancy, isoserologic incompatibilities and other
The edition is intended for obstetrician-gynecologists.
