Indican (animal) - alkaline salt intoxicates acid. It is synthesized in the liver of sulfur-containing compounds, resulting in protein oxidation of sulfur (cysteine) and from the oxidation product of indole (see) - indoxyl. In normal conditions the content of indican in urine is low, but increases significantly with enhanced processes of decay in the gut (for example, when obstruction of the small intestine), with a significant breakdown of proteins (for example, malignant tumors). In these cases, the quantitative determination of indican in the urine has diagnostic value (see the Urine).