Infiltration is a seal in the tissue or organ (subcutaneous tissue, muscles, the lung, liver), resulting from the accumulation of cellular elements of blood and lymph. In acute inflammation infiltration occurs because of the rapid multiplication of cells of the tissue, the emergence of a large number of leukocytes, lymphocytes, sweating from the blood vessels of plasma of blood and lymph. Tissue infiltration increases in volume, changes color, becoming tight, painful. Under certain chronic infections (tuberculosis, syphilis, a actinomycosis) infiltrate develops at the site of the introduction of pathogen mainly due to cell multiplication of local connective tissue.
When surgery infiltrate created artificially during anesthesia by soaking fabrics procaine or other painkiller (see Anesthesia).
The outcome of the infiltrate is different depending on the nature of the process that caused his education, particularly tissue, the degree of reactivity of the organism. Inflammatory infiltrate in case of timely elimination of the reasons and rational treatment can dissolve, and otherwise in its place is formed abscess (see). In chronic infections are characterized by necrosis in the centre of infiltration, leading to the formation of fistulas.