Itsenko - Kushinga disease

Itsenko - Kushinga disease - a disease caused by defeat of the hypothalamic-pituitary area with a secondary increase in the formation of hormones napochechnikov crust. Symptoms of a disease Itsenko - Kushinga can be observed also in other pathological States, which are accompanied by increased formation of hormones crust napochechnikov (tumor of the adrenal cortex, it hyperplasia, and so on). In these cases syndrome, unlike disease Itsenko - Kushinga with the primary defeat of the hypothalamic-pituitary area, called the "syndrome Itsenko - Kushinga".
The disease usually progresses slowly. Growing weakness, fatigue, headaches. See the obese individuals, excessive deposition of fat on the body, except the extremities. The skin of the face crimson, trunk - dry, with a purple marble figure a lot of acne. The skin of the abdomen, chest, armpit, and so on, broad band crimson red. Women are progressing hirsutism (see), amenorea (see), and in men impotence (see). Characterized by increased blood pressure, osteoporosis. Broken all kinds of metabolism, mainly carbohydrate and protein.
Complications: bleeding in the brain, stenocardia, myocardial infarction, heart failure, spontaneous fractures.
The diagnosis is based on a typical clinical picture (must be differentiated from tumors of the adrenal cortex).
Treatment - radiotherapy, if necessary, surgical treatment (total bilateral adrenalectomy). Symptomatic funds (hypotensive, tireoidin - in obesity, estrogens - by aplasia of sexual glands in women).