Clinical classification of rheumatism

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One of the important functions of enzymes is mediating neural and neuroendocrine effects on tissue metabolism. In this connection, of interest the results of a study of some indicators of the state of the nervous system, characterizing different course options rheumatism. In our research in 70 patients with active phase of the disease studied glitseridy reflex, ortho - and conotations trial, the state of skin and temperature topography on Shargorodsky, sweating on the minor. In 200 patients with primary rheumatism revealed signs asthenia nervous system and determined the status of thermoregulation. It was established that violations of thermoregulation, vegetative samples symptoms of asthenia nervous system is most frequently observed in prolonged and continuous recurrent rheumatic fever and is not characteristic for its acute and subacute options. These data correlate with the results of the EEG studies. Clearly revealed the predominance of electroencephalograms (EEG) violations of bioelectric activity of the brain during prolonged for rheumatism could testify, according to modern ideas, and greater severity of Central regulatory disorders in patients specified clinical group.
The problem deregulation is one of the priority problems in the study of the pathogenesis of rheumatic fever. There is no doubt that an important role in the origin of regulatory disorders belongs external influences, among which of special importance streptococcal infection, the repeated attacks of the disease modifying reactive capacity of the organism to unfavorable direction. Along with this, in the clinic of the dependence of the nature of the flow of rheumatic processes and genetic factors associated with gender and age. With the help of special electroencephalographic studies of close relatives of patients with rheumatism it is also shown that the nature of the disease, apparently, is based on inherited the individual characteristics of the functional state of some of the formations of the brain. Thus, a comprehensive research has shown that the nature of the flow of rheumatic fever is defined by the previous and emerging in the course of the disease condition reactivity of the patient, i.e. acquired and, apparently, constitutional qualities of its protective and compensatory systems.
In the last column of the working classification (see table. 2) presents the nomenclature for the functional characteristics of the blood Strazhesko - Vasilenko with the division of circulatory failure on I, IIA, IB and III stage.
A working classification allows to estimate rheumatism as multifaceted disease in a particular patient, noting the phase of arthritis at the time of the survey with the degree of differentiation of activity, with the indication of primary or recurrent nature of the rheumatic process, with detailed enumeration of the localization of the pathological process and the forecast in connection with the characteristics of the course. Such a deep understanding of the pathological process helps the physician in determining the course at the time of the survey, and in the organization of dispensary milestone surveillance.