Chelating agents - organic substances (mainly aminopolicarboxylates acids and their salts)that form with ions of metals non-ionizing resistant water-soluble complexes. This property chelating agents used in medical practice for deducing from an organism of polyvalent cations of metals; separation occurs primarily via the kidney , and to a lesser extent through the intestines. As the drugs used are the following.
Tetatsin-calcium (Tetacinum-calcium; synonym calcium-disodium salt EDTA, CaNa2 EDTA; list B) assign inside and intravenous in both acute and chronic poisoning and heavy rare earth elements (lead, cadmium, cobalt, mercury, uranium and others). Single dose for intravenous drop injection, 2 g (40 ml of 5% or 20 ml of 10% solution), daily 4, Inside appoint 2 g (0.5 g 4 times a day).
Pentatsin (Pentacinum; synonym calcium-dinatrieva salt diethylenetriaminepentaacetic acid; list B) used in acute and chronic poisoning plutonium, radioactive yttrium, cerium, zirconium. Injected 5 ml, in severe cases, up to 30 ml of 5% solution.
Disodium salt ethylenediaminetetraacetic acid (synonym: Trilon B, Na2 EDTA; list B) apply in cases involving excessive accumulation of salts of calcium in the body (arthritis deposition of salts, scleroderma and other). Injected 2-4 g of the preparation dissolved in 500 ml of 5% glucose solution, drip for 3-4 hours.