Lipochrome (gr. lipos fat + granuloma; synonym: oleogranulomas, paraffinum) focal chronic inflammation at the injection fat or adipose tissue necrosis due to injury, inflammation, ischemia and other
There are artificial (injection) of lipogenesis, traumatic (for example, in newborns), inflammatory and ischemic (for example, after typhus). Lipogenesis can occur not only in fatty tissue, but also in internal organs, such as the lungs (lipoid pneumonia). There is also spontaneous common lipogranulomatosis or recurrent ninagaagiye knotted panniculitis (see Weber - Christian disease).
Macroscopically lipogenesis are kind of tough hilly site. If the node is located under the skin, the latter is usually unchanged. On a cut in Leningrad often defined cystic cavities made fat.
Histologically find granulation tissue with the availability of multi-core giant lipoflow and santonij cells and cysts, lined with large cells containing fat. Fresh gipohromnah determined foci of necrosis of adipose tissue. In the long-existing L. dominated by fibrous tissue with Santanyi cells and giant multi-core lipofile. Sometimes in Leningrad there are bumps, reminiscent of the observed tuberculosis or sarcoidosis. Such changes may be associated with allergic autoimmune processes.
Despite the fibrosis, lipochrome has a tendency to slow progression of involvement in the process of surrounding tissues, so the self-recovery occurs rarely. Sometimes in the subcutaneous L. due to inflammatory and necrotic processes occur long not healing fistula. The outcome of lipogenesis can be calcification (see).
The treatment is surgical excision of lipogenesis in healthy tissues.