Lipomatosis - excessive deposition of fat in adipose tissue, most often in the subcutaneous. In some cases, the fat is deposited evenly (see Obesity), in others there segmental obesity upper, middle or lower part of the body. Clinical observations suggest in most cases the dependence segmental lipomatosis from endocrine disorders.
In addition to the General conditions, obesity, allocate specific localised fat - lipoma (see), a disease Dercum observed in menopausal women (see Obesity). When the disease appear knotted, painful fatty diameter from 5 up to 10 cm on the hips, abdomen, upper extremities. Histologically nodules are characterized by abundant development of vascular network than they are like angiolipoma. General changes consist of endocrine glands atrophy, osteoporosis and violations from the side of neuropsychic sphere of patients.
Emphasize the syndrome of Madelung, where there are diffuse, multiple, painful growths of adipose tissue in the area of the lymph nodes in the neck. At strongly expressed syndrome Madelung patients complain sharp thickening of the neck, pain, difficulty in breathing and dysphagia. Some authors point to a connection between the syndrome of Madelung deficiency of the thyroid gland, the other - with the primary lymph nodes in the neck or with a tendency to neurodystrophic processes in adipose tissue. The only method of treatment of a syndrome of Madelung - surgical excision growths adipose tissue. Describe the recurrence after surgical excision.
General treatment of any form of lipomatosis includes the use of the hormonal and organotherapeutic drugs and must be pathogenetically substantiated.