Liposarcoma (gr. lipos fat + sarcoma; synonym: petalochilidae lipoma, infiltrating lipoma, liponexol, mikamika) is a malignant tumor growing from the adipose tissue. It occurs in both sexes, regardless of age, in any part of the body that contains fat, but most often is observed on the lower extremities and in the retroperitoneal area.
Liposarcoma is usually a tumor of considerable size, as a rule, well defined, but not completely surrounded by a capsule; in the context of yellow, grainy, with foci of necrosis and hemorrhage. When intermuscular the growth of the tumor thick, pale, the cut is allocated transparent viscous liquid.
Microscopically, the tumor is composed of clusters of large spindle-shaped cells, sometimes shaped "mulberry" and containing in the cytoplasm of numerous granules neutral fat. Marked polimorphism cells, numerous figures mitoses. Intermuscular type liposarcoma resembles a lipoma (see), containing a large number sarcomatoid cells, some of them have spider species, in selected areas, the tumor contains a large amount of mucus.
Liposarcoma is usually found by accident when you reach large sizes. During the inspection and palpation of this soft-elastic, separated, lobed the tumor with granular surface.
In some cases, the diagnosis can help Cytology punctate tumors. Liposarcoma give early widespread metastases. Some species are more likely to yield relapses, metastasize slowly.
The main method of treatment is extensive surgical removal of the tumor within healthy tissue. Postoperative radiotherapy may be useful, especially for recurrent tumors.