Lipotropic substances

Lipotropic substances (from the Greek. lipos - fat and trepo - turn, turn) - compounds with the ability to prevent fatty infiltration of the liver that occurs in both animals and humans under the influence of some factors. Among the most active lipotropic substances are choline (see), methionine (see), Inositol (see), lecithins (see), casein (see)methylated derivatives purines (caffeine), and also preparations of the pancreas (see Lipokain). The introduction of these compounds in the body eliminates or drastically reduces the degree of obesity , the liver, resulting in disturbances of external secretion of the pancreas, with an endogenous or exogenous protein deficiency, with long-term consumption of foods containing large amounts of lipids, including cholesterol, and with increased education in the liver of fats from carbohydrates under the influence of vitamin B1 or other factors.
The mechanism of action of these lipotropic substances not fully clarified. All these lipotropic substances vary considerably in strength lipotropic action, the expression of it in obesity liver of different origin. However, they all have an effect in cases of obesity liver that is caused or increased synthesis in the liver of fats from carbohydrates, or breach of transport of fatty acids from the liver into the fat depot. In cases of obesity, which is caused by the strengthening of the transfer of fat from fat depots in the liver (introduction extracts the anterior pituitary, phosphorus poisoning or carbon tetrachloride)specified L. C. either not effective or have very little effect.