Magnesium

Magnesium (Magnesium, Mg) - the element of the second group of the periodic system D. I. Mendeleev, number 12, atomic weight 24,32, valence +2. Silvery-white metal. Magnesium plays an important role in the life of organisms (part of several enzyme systems). The ingestion magnesium resorptive do not because they are poorly absorbed from the stomach and intestines (manifested osmotic effect - laxative effect). Salts of magnesium have choleretic effect. When parenteral introduction of salts of magnesium depress the Central nervous system (causing sopivasti, numbness, paralysis of skeletal muscles and anesthesia), relaxes the smooth muscles and act spazmolitichesky. With the increased consumption of magnesium in a long time there is an increase in the allocation from the body of calcium. Highlights salts of magnesium from the body through the intestines and kidneys.
Preparations of magnesium. Magnesium sulfate (Magnesium sulfuricum, Magnesii sulfas; synonym bitter salt - Sal amarum). Used as a sedative, spasmolytic, anti - laxative and cholagogue. 25% solution of magnesium sulfate give muscles for 5 - 20 ml at hypertensive disease (treatment 15-20 days), while toxicosis of pregnancy (with caution, as oppressed the ability Oxytocics Oxytocics), and convulsions. As a laxative assign inside of 10 to 30 grams in a glass of water (children - at the rate of 1 g per 1 year) and in enemas (100 ml 20-30% solution). As zhelchegonnoe used inside on 1 table. L. 20-25% solution 3 times a day. When duodenal intubation probe is inserted through 50 ml of 25% or 100 ml of 10% solution. In lead colic and urinary retention is introduced as antispasmodic in muscle (5-10 ml 10-20% solution), in Vienna (5 to 10 ml of 5% solution) or by enema. In case of poisoning by mercury, arsenic, a tetraethyl lead is injected into a vein 5-10 ml 5-10% solution, with poisoning soluble salts of barium washed stomach 1% solution or give into 20 to 25 grams in a glass of water. Parenteral magnesium sulfate should be used with caution, given the possibility of respiratory depression. In case of respiratory depression in the vein type calcium chloride (5-10 ml 10% solution). Method of production: powder and capsules of 2, 5, 10 and 20 ml of 25% solution.
Oxide magnesium oxydatum, Magnesii oxydum; synonym burnt magnesia, Magnesia usta) - antacid means. Applied inside the high acidity gastric juice (of 0.1 - 1 g), in the administration acids and as a laxative (3-5 g).
Magnesium carbonate core (Magnesium subcarboni-cum, Magnesii subcarbonas; SNN. basic magnesium carbonate). Use as a laxative (1 - 3 g), antatsidnye means and externally in the form of powder. Cm. also Antacid.

Magnesium (Magnesium, Mg) is a chemical element with the second group of the periodic system of elements of D. I. Mendeleyev. Silvery-white metal. Famous 3 sustainable and 3 of the radioactive isotope. Valence-2. When burning passes into magnesium oxide MgO (burnt magnesia). Salt M (chloride M, MgCl2 and others) colorless, many soluble in water and have a bitter-salty taste. Under the action of alkali solutions of salts M hydroxide is formed M. [Mg(OH)2]. Magnesium is widely distributed in nature and plays an important role in the life of organisms. Regular food M. contains sufficient for the body. Daily demand adult M is approximately 10 mg/kg of body weight. In children, as well as during pregnancy and lactation this need above. With the increased consumption Meters for a long time there is increased release of calcium from the body in the result of the displacement his Feet Violation magnesium-calcium balance in the body occurs in rickets, when the number of Meters in the blood decreases due to the fact that he goes into the bone, displacing calcium. The normal concentration Meters in the blood is about 4.3 mg%. With increased content M. in the blood are drowsiness, numbness, paralysis of skeletal muscles and can even come deep anaesthesia (captured by the introduction of calcium). Meters from the body write largely through the intestine and less urine.
Preparations of magnesium. 1. Magnesium sulfate (Magnesium sulfuricum). Used as a sedative, protivosudorozhnoe, skin, laxative and cholagogue. To reduce blood pressure in hypertensive drug is injected intramuscularly 5-20 ml of 25% solution every day for 15-20 days. When nephropathy pregnant intramuscular injection of 20 ml 25% solution 4 times a day. As a laxative sulfate PM is appointed into adults 10-30 grams in a glass of water, children at the rate of 1 g per year of life. Chronic constipation is used enemas from 100 ml 20-30% solution. As cholagogue sulfate M used inside in the form 20 - 25% solution of 1 table. L. 3 times a day. When duodenal intubation with the same purpose introduce a 50 ml of 25% or 100 ml of 10% solution. As a spasmolytic agent (in lead colic, the delay urination) sulfate PM intramuscularly 5-10 ml 10-20% solution or intravenous 5-10 ml of 5% solution.
Magnesium sulfate is also used for treatment of poisoning. In chronic poisoning by mercury, arsenic, tetraethyl lead (TPP) its injected 5-10 ml 5-10% solution. In case of poisoning soluble salts of barium the agent shall inside to 25 grams in a glass of water.
Parenteral apply sulfate PM carefully, given the possibility of respiratory depression. In cases of respiratory depression, give intravenous calcium chloride (5-10 ml 10% solution). In the appointment of sulfate PM pregnant you must reckon with the danger of oppression contractile uterine musculature. Method of production: powder and capsules of 2, 5, 10 and 20 ml of 25% solution.
2. Magnesium oxide (Magnium oxydatum; synonym: burnt magnesia - Magnesia usta) - antacid means. Applied inside the high acidity gastric juice (of 0.1 - 1 g), and as a laxative (3-5 g).
3. Magnesium carbonate core [Magnium carbonicum basicum; synonym: main carbonic M (Magnium carbonicum, MgCO3+Mg(OH)2]. Used as a laxative (1-3 years) and as a powder as anti-acid agent.