Meningitis caused by coccidia

The disease is caused by a gram-positive pathogenic fungus (Coccidioides immitis). Hematogenous spread of the fungus in the body causes disseminated process with damage to various organs (lungs, bones and other). At hit of fungus into the subarachnoid space of the developing nervous system, the most common form is meningitis. The inflammatory process in the soft brain membranes at the monastery, caused by coccidia, has many similarities with TB M thick shells, more on the base of the brain, there are multiple small granulomas composed of lymphocytes, plasma cells, macrophages and giant cells. Pathogenic fungi are intra - and extracellular, forming thick round education, containing endospores. Clinical symptoms of meningitis develop abruptly, beginning with a sharp headaches and vomiting. May develop convulsions, impaired consciousness, the emergence of paralysis of the extremities, the defeat of the cranial nerves. The pressure of the cerebrospinal fluid is increased, Placitas mainly lymphocytic to several hundred cells of 1 mm3, moderately increased protein content. It is possible to select from the cerebrospinal fluid culture of coccidia. The disease is a chronic course duration is 4 months and more. The forecast of serious, often comes death. Differential diagnosis with TB meningitis is difficult. Critical to the diagnosis has a selection of coccidia from the cerebrospinal fluid. Treatment of symptomatic.