Meningitis caused by Leptospira

In the USSR, are 16 serological types Leptospira pathogenic for humans. The main source of the infection are rodents. Leptospira enter the body of a man often through the skin and hematogenous spread. Infection occurs when bathing in infected leptospirae water, when walking barefoot in the swampland. Possible and nutritional route of infection by drinking infected water or milk from animals suffering Icterohaemorrhagiae. At hit of leptospires in the subarachnoid space occurs leptospirosis meningitis or meningoencephalitis. Anatomically expressed in the phenomenon serous or purulent M, often with subarachnoidal hemorrhages.
Clinically development of meningitis preceded by fever, chills, muscle aches, headaches, rashes, herpes, vascular disorders. After a few days of acute develop meningeal symptoms with sharp headaches and vomiting. Leptospirosis M has more severe character, but can be and purulent. The pressure of the cerebrospinal fluid is increased, the protein content is moderately increased, Placitas from 20 to 500 cells in 1 mm3; cell - mostly lymphocytes. Observed and neutrophilic Placitas, reaching several thousand cells. The sugar content in the normal range. Lumbar puncture facilitates the condition of patients. Symptoms of meningitis can be combined with the paralysis of cranial nerves, pyramidal symptoms with paralysis of the extremities, etc. For leptospiroses M 5-20 days, but the rehabilitation of cerebrospinal fluid and recovery focal symptoms come later. The forecast is favorable. Long pronounced post-infectious asthenic syndrome. The diagnosis is confirmed epidemiological data and agglutination reaction to the culture Leptospira. Recommended dehydration treatment (intramuscular injection of 25% solution of magnesium sulfate, intravenous infusion of 40% glucose solution), injections of penicillin, symptomatic treatment. Shows a strict bed rest and a dairy-vegetarian diet.