Nanism (synonym: dwarfism, microsomia) is characterized by a small growth (below 130 cm).
Nanism can be independent disease (hypophyseal nanism) or a symptom of some endocrine and other diseases (hypothyroidism syndrome Shereshevsky-Turner , chondrodystrophy , and so on). In addition, growth and human development can be influenced by genetic factors, insufficient or malnutrition, adverse environmental conditions.
Hypophyseal nanism (synonym hypophyseal dwarfism) is a disease that is caused by insufficient production of somatotropic, gonadotropic, often adrenocorticotropic and thyroid-stimulating hormone and lowering the functions of the corresponding endocrine glands.
The reason hypophyseal nanism can be pathological process in the hypothalamic-pituitary region (tumor, infection, gum, and so on).
Hypophyseal nanism characterized proportioned with low growth, a sharp underdevelopment of the reproductive system, the lack of secondary sexual characteristics, small size of the internal organs, of sound mind. The size of the Turkish saddle in the presence of pituitary tumors can be increased.
Treatment hypophyseal nanism depends on the cause of the disease. When identifying pituitary tumors spend radiotherapy or surgical removal of the tumor. Currently widespread synthetic anabolic steroids - methylandrostendiolappointed sublingual based 1-1 .5 mg/kg per day; methandrostenolone (nerobolum)designated inwards or probaly, retabolil - parenteral dosage, depending on age, etc. Treating growth hormone is currently very limited. If symptoms indicating the failure of function of glands of internal secretion, conduct appropriate substitution therapy (tireoidin, glukokortikoida and so on). The nutrition of patients with pituitary nanism should be complete with enough protein and vitamins. Treatment of nanism as a symptom should be aimed at addressing the underlying disease. The forecast is favorable for life.