Narcotic drugs

Drugs - group medicinal substances, used for narcosis (see).
Depending on a way of introduction into the organism of a drug divided into inhalation and neingaltine. Inhalation drugs entered via the respiratory tract in a mixture with air or oxygen, are volatile liquids (Narrogin, halothane, chloroform, chloroethyl, ether for narcosis) or gases (nitrous oxide, cyclopropane). Neingalip drugs are used usually for intravenous (geksenal, Tibetan, thiopental sodium, issued a foreign, sodium oxybutyrate) and rectal narcosis (narkoman).
Drugs have a predominant influence on the Central nervous system, invoking oppression of its activities in breach of synaptic transmission. Different structures of the brain have different sensitivity to drugs, so their oppression when the concentration of drugs in the blood occurs not at the same time. First of all suppressed functions of the higher departments of the Central nervous system. The most resistant to drugs vital centers of the medulla oblongata - the respiratory and vasomotor.
For anaesthesia at the required level is regulated by the entry of drugs into the body by changing the concentration of inhalation of drugs in the mixture of asbestos or speed intravenous neingaltine narcotic drugs. Managing the depth of anesthesia is facilitated by the use of inhaled drugs than in the application neingaltine. When the supply of narcotic drugs to their concentration in the blood is declining rapidly due to selection unchanged through the lungs (inhalation drugs) or fast destruction in the body (geksenal, Tibetan, thiopental sodium). At least reduce the concentration of drugs in the blood revival - restored muscle tone and suppressed during anaesthesia reflexes, receive sensitivity, returning consciousness. After waking up usually comes a dreamthat can last for several hours.
Drugs used for anesthesia in surgical interventions for the treatment of pain in myocardial infarction and in the postoperative period (nitrous oxide), during labor pain relief, as well as edema of convulsive States (in case of poisoning by strychnine and other convulsive toxins). Contraindications to the use of narcotic drugs are associated with primary toxic effect of one or another narcotic drugs on different organs and systems. Ether is not suitable for tuberculosis and other diseases of the lungs and respiratory tract; chloroform - at illnesses of a liver and kidneys; halothane - when expressed arrhythmias, liver diseases; nitrous oxide - by States, in which is especially dangerous oxygen starvation; cyclopropane - when arrhythmias; geksenal, Tibetan, thiopental sodium - for violations of the liver and kidneys.
Using an inhaled drug, it should be considered that a pair of air of flammable and form explosive mixtures with oxygen and air, chloroethyl flammable, nitrous oxide is not flammable, but will support combustion. Chloroform and halothane not flammable.
An overdose of narcotic drugs sharp oppression or paralysis of the respiratory and vasomotor centers. In this case it is necessary to stop the flow of drugs (when using the inhalation of drugs or drug intravenous drip method), to establish artificial respiration (controlled), conduct oxygen therapy, assign parenteral stimulants respiratory and circulatory - korazol, bemegride, kordiamin, caffeine, tsititon, lobeline, strofantin, epinephrine, norepinephrine, ephedrine, mezaton. Halothane, cyclopropane, and chloroform increase the sensitivity of the myocardium to adrenaline, so avoid fibrillation when using these drugs, you cannot enter the adrenaline and noradrenaline. For reducing the concentration of drugs in the blood in severe cases, it is advisable transfusion of blood or the introduction of blood fluids.
Individual drugs - see the article by name drugs.