Neomycin is an antibiotic produced during the life of radiant fungus (aktinomiceta). Neomycin is effective against a number of grampolaugitionah (staphylococci, pnevmokocchi, streptococci , and others) and gramotricationah (Escherichia coli, Bacillus dysentery, Protey and others) microbes, including those resistant to other antibiotics. Resistance to neomycin develops slowly and in small degree. For medical purposes use neomycin sulfate (Neomycini sulfas; list B). Testimony to the use of the drug are pneumonia, including pneumonia in newborns, Coelenterata, purulent-septic diseases, mastitis, endometritis, meningoencephalitis, cystitis, piodermii, infected wounds, ulcers and other designated neomycin inside and externally. Intramuscular in view of the toxicity of the drug is allowed in exceptional cases. Externally for wetting tampons, bandages, for irrigation and drops using solutions containing 5000 ED neomycin in 1 ml (once no more than 25-50 ml). Inside neomycin appoint 100 000-200 000 IU 2 times a day. When administered neomycin may arise diarrhoeal disorders, allergic reactions, and when parenteral use, damage to the kidneys and the hearing nerve. Kidney disease (principally, jade) and auditory nerve application neomycin is contraindicated.
Method of production: powder in sealed vials containing 200 000 and 400 000 and 800 000 UNITS of the drug, and tablets of 100 000 and 200 000 IU. Cm. also Antibiotics.