Neurofibromatosis (synonym Recklinghausen's disease) is a systemic disease, which occur multiple tumor nodes along the nerves and nerve endings in the skin and dark spots on the skin. More common in men, usually occurs in early childhood. Tumor nodes and the spots of color of coffee with milk (or brownish various sizes) are usually on the back, chest, neck, and sometimes on the limbs. The size of the tumor nodes in the skin and subcutaneous tissue is not large (1 to 1.5 cm), have a spherical shape, can rise above the surface of the skin, thick consistency, sometimes slightly painful. Rarely malignant nodes reach the huge sizes, usually speaks of malignant degeneration.
Pain patients usually do not experience. With the defeat of nervous trunks neurofibromatosis nodes can be single in form egg-shaped solid tumors in the neck or thigh, often affects the nerve plexus (shoulder shoulder) and sciatic nerve.
In multiple lesions of the nerve trunk formed several nodes in the form celabrate thickening along the nerve. Neurofibromatosis can be expressed in the form of tumor growths of the skin and subcutaneous tissue hanging uneven, often multiple folds of skin; they have a soft texture, often pigmented. Typically this form of neurofibromatosis observed on the head and neck and is called elephantiasis (neuropathy elephantiasis).
During neurofibromatosis long, benign, but progressive. Possible malignant regeneration of separate units in neurogenic sarcoma and the development of metastases.
Neurofibromatosis can be combined with malformations or other tumors (angioma, lipoma and others).
Radical treatment is absent. Appropriate surgical removal of the tumor those sites which have been growing rapidly, causing pain, squeeze vital organs or suspicious for cancer that develops.